Pemencilan komponen rotundona terbaharu daripada akar croton hirtus (euphorbiaceae)

Translated title of the contribution: Isolation of new rotundone from the roots of croton hirtus (Euphorbiaceae)

Andi Rifki Rosandy, Anis Asmi Azman, Rozida Mohd. Khalid, Rizafizah Othaman, Mohamad Azwani Shah Mat Lazim, Iqbal M. Choudary, Yana Maulana Syah, Jalifah Latip, Ikram M. Said, Muntaz Abu Bakar

Research output: Contribution to journalArticle

Abstract

Croton is a genus of Euphorbiaceae which consists of approximately 1,300 species and are widely distributed in Asia, Africa and South America. Phytochemical study on the root of Croton hirtus has been conducted. The powder of the root of C. hirtus was extracted using the methanol solvent at room temperature for 24 hours and repeated three times. The crude extracts obtained were analysed using thin layer chromatography (TLC) then fractionated via vacuum column chromatography (VLC) and proceed the isolation using radial chromatography (RC) to get the pure compounds. The pure compounds obtained were elucidated by nuclear magnetic resonance (NMR), Fourier transform infrared (FT-IR) and mass spectroscopy to confirm their structures and from that analysis, the compounds were identified as two new compounds naming (+)5,14-dihydroxyrotundone-9-(2’-methybut-2’-enoate) (1) and (-)5,14-dihydroxyrotundane-9-benzoate (2) with total weight 135 mg and 145 mg respectively. This two compound were reported for this time on this genus.

Original languageMalay
Pages (from-to)677-681
Number of pages5
JournalMalaysian Journal of Analytical Sciences
Volume23
Issue number4
DOIs
Publication statusPublished - 1 Aug 2019

Fingerprint

Thin layer chromatography
Column chromatography
Benzoates
Phytochemicals
Chromatography
Complex Mixtures
Powders
Methanol
Fourier transforms
Nuclear magnetic resonance
Spectroscopy
Vacuum
Infrared radiation
Temperature
rotundone

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Pemencilan komponen rotundona terbaharu daripada akar croton hirtus (euphorbiaceae). / Rosandy, Andi Rifki; Azman, Anis Asmi; Mohd. Khalid, Rozida; Othaman, Rizafizah; Mat Lazim, Mohamad Azwani Shah; Choudary, Iqbal M.; Syah, Yana Maulana; Latip, Jalifah; Said, Ikram M.; Abu Bakar, Muntaz.

In: Malaysian Journal of Analytical Sciences, Vol. 23, No. 4, 01.08.2019, p. 677-681.

Research output: Contribution to journalArticle

@article{ecbdfe186c324feeab608a1d89f25761,
title = "Pemencilan komponen rotundona terbaharu daripada akar croton hirtus (euphorbiaceae)",
abstract = "Croton is a genus of Euphorbiaceae which consists of approximately 1,300 species and are widely distributed in Asia, Africa and South America. Phytochemical study on the root of Croton hirtus has been conducted. The powder of the root of C. hirtus was extracted using the methanol solvent at room temperature for 24 hours and repeated three times. The crude extracts obtained were analysed using thin layer chromatography (TLC) then fractionated via vacuum column chromatography (VLC) and proceed the isolation using radial chromatography (RC) to get the pure compounds. The pure compounds obtained were elucidated by nuclear magnetic resonance (NMR), Fourier transform infrared (FT-IR) and mass spectroscopy to confirm their structures and from that analysis, the compounds were identified as two new compounds naming (+)5,14-dihydroxyrotundone-9-(2’-methybut-2’-enoate) (1) and (-)5,14-dihydroxyrotundane-9-benzoate (2) with total weight 135 mg and 145 mg respectively. This two compound were reported for this time on this genus.",
keywords = "Croton hirtus, Euphorbiaceae, Rotundone",
author = "Rosandy, {Andi Rifki} and Azman, {Anis Asmi} and {Mohd. Khalid}, Rozida and Rizafizah Othaman and {Mat Lazim}, {Mohamad Azwani Shah} and Choudary, {Iqbal M.} and Syah, {Yana Maulana} and Jalifah Latip and Said, {Ikram M.} and {Abu Bakar}, Muntaz",
year = "2019",
month = "8",
day = "1",
doi = "10.17576/mjas-2019-2304-14",
language = "Malay",
volume = "23",
pages = "677--681",
journal = "Malaysian Journal of Analytical Sciences",
issn = "1394-2506",
publisher = "Faculty of Science and Technology, Universiti Kebangsaan Malaysia",
number = "4",

}

TY - JOUR

T1 - Pemencilan komponen rotundona terbaharu daripada akar croton hirtus (euphorbiaceae)

AU - Rosandy, Andi Rifki

AU - Azman, Anis Asmi

AU - Mohd. Khalid, Rozida

AU - Othaman, Rizafizah

AU - Mat Lazim, Mohamad Azwani Shah

AU - Choudary, Iqbal M.

AU - Syah, Yana Maulana

AU - Latip, Jalifah

AU - Said, Ikram M.

AU - Abu Bakar, Muntaz

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Croton is a genus of Euphorbiaceae which consists of approximately 1,300 species and are widely distributed in Asia, Africa and South America. Phytochemical study on the root of Croton hirtus has been conducted. The powder of the root of C. hirtus was extracted using the methanol solvent at room temperature for 24 hours and repeated three times. The crude extracts obtained were analysed using thin layer chromatography (TLC) then fractionated via vacuum column chromatography (VLC) and proceed the isolation using radial chromatography (RC) to get the pure compounds. The pure compounds obtained were elucidated by nuclear magnetic resonance (NMR), Fourier transform infrared (FT-IR) and mass spectroscopy to confirm their structures and from that analysis, the compounds were identified as two new compounds naming (+)5,14-dihydroxyrotundone-9-(2’-methybut-2’-enoate) (1) and (-)5,14-dihydroxyrotundane-9-benzoate (2) with total weight 135 mg and 145 mg respectively. This two compound were reported for this time on this genus.

AB - Croton is a genus of Euphorbiaceae which consists of approximately 1,300 species and are widely distributed in Asia, Africa and South America. Phytochemical study on the root of Croton hirtus has been conducted. The powder of the root of C. hirtus was extracted using the methanol solvent at room temperature for 24 hours and repeated three times. The crude extracts obtained were analysed using thin layer chromatography (TLC) then fractionated via vacuum column chromatography (VLC) and proceed the isolation using radial chromatography (RC) to get the pure compounds. The pure compounds obtained were elucidated by nuclear magnetic resonance (NMR), Fourier transform infrared (FT-IR) and mass spectroscopy to confirm their structures and from that analysis, the compounds were identified as two new compounds naming (+)5,14-dihydroxyrotundone-9-(2’-methybut-2’-enoate) (1) and (-)5,14-dihydroxyrotundane-9-benzoate (2) with total weight 135 mg and 145 mg respectively. This two compound were reported for this time on this genus.

KW - Croton hirtus

KW - Euphorbiaceae

KW - Rotundone

UR - http://www.scopus.com/inward/record.url?scp=85071359099&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071359099&partnerID=8YFLogxK

U2 - 10.17576/mjas-2019-2304-14

DO - 10.17576/mjas-2019-2304-14

M3 - Article

AN - SCOPUS:85071359099

VL - 23

SP - 677

EP - 681

JO - Malaysian Journal of Analytical Sciences

JF - Malaysian Journal of Analytical Sciences

SN - 1394-2506

IS - 4

ER -