Is there a relationship between bone mineral density, mammographic breast density and serum estrogen concentration level? Study on Malaysian women

N. M. Zain, Kanaga Kumari Chelliah, Elda Surhaida Latif, A. Shantini

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Estrogen is known to affect both mammographic breast density and bone mineral density. Breast density is a well-known risk factor of breast cancer determined by the physiological hormonal changes. Studies shown inconclusive relationship of breast density and bone mineral density as breast cancer risk factors. This study aimed to determine the relationship of bone mineral density; mammographic breast density and serum estrogen concentration level in Malaysian women. A cross sectional study on 108 women aged above 40 years who underwent bone scan and mammography screening was conducted at the General Hospital Kuala Lumpur from 2016 to 2017. Subjects were chosen using convenient sampling technique. With women commenced cancer treatment and women who had mastectomy done being excluded from the study. An independent-t and chi-square statistical test were used to analyze the continuous and categorical data whilst binary logistic regression was used to determine the mentioned relationship. A total of 75.5% of the respondents had a normal bone mineral density in the hip and 76.9% in the spine. Abnormality in bone mineral density were recorded to be higher in postmenopausal women with the bone mineral density in spine (23.2%) region were slightly higher compared to the hip (18.5%). There was no statistical significant relationship between mammographic breast density and serum concentration level with bone mineral density in hip and spine.

Original languageEnglish
Title of host publication2nd International Conference for Innovation in Biomedical Engineering and Life Sciences - ICIBEL 2017 in conjunction with APCMBE 2017
PublisherSpringer Verlag
Pages259-263
Number of pages5
Volume67
ISBN (Print)9789811075537
DOIs
Publication statusPublished - 1 Jan 2018
Event2nd International Conference for Innovation in Biomedical Engineering and Life Sciences, ICIBEL 2017, held in conjunction with the 10th Asia Pacific Conference on Medical and Biological Engineering, APCMBE 2017 - Penang, Malaysia
Duration: 10 Dec 201713 Dec 2017

Other

Other2nd International Conference for Innovation in Biomedical Engineering and Life Sciences, ICIBEL 2017, held in conjunction with the 10th Asia Pacific Conference on Medical and Biological Engineering, APCMBE 2017
CountryMalaysia
CityPenang
Period10/12/1713/12/17

Fingerprint

Minerals
Bone
Estrogens
Mammography
Oncology
Statistical tests
Logistics
Screening
Sampling

Keywords

  • Bone mineral density
  • Estrogen
  • Mammographic breast density

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

Cite this

Zain, N. M., Chelliah, K. K., Latif, E. S., & Shantini, A. (2018). Is there a relationship between bone mineral density, mammographic breast density and serum estrogen concentration level? Study on Malaysian women. In 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences - ICIBEL 2017 in conjunction with APCMBE 2017 (Vol. 67, pp. 259-263). Springer Verlag. https://doi.org/10.1007/978-981-10-7554-4_45

Is there a relationship between bone mineral density, mammographic breast density and serum estrogen concentration level? Study on Malaysian women. / Zain, N. M.; Chelliah, Kanaga Kumari; Latif, Elda Surhaida; Shantini, A.

2nd International Conference for Innovation in Biomedical Engineering and Life Sciences - ICIBEL 2017 in conjunction with APCMBE 2017. Vol. 67 Springer Verlag, 2018. p. 259-263.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zain, NM, Chelliah, KK, Latif, ES & Shantini, A 2018, Is there a relationship between bone mineral density, mammographic breast density and serum estrogen concentration level? Study on Malaysian women. in 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences - ICIBEL 2017 in conjunction with APCMBE 2017. vol. 67, Springer Verlag, pp. 259-263, 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences, ICIBEL 2017, held in conjunction with the 10th Asia Pacific Conference on Medical and Biological Engineering, APCMBE 2017, Penang, Malaysia, 10/12/17. https://doi.org/10.1007/978-981-10-7554-4_45
Zain NM, Chelliah KK, Latif ES, Shantini A. Is there a relationship between bone mineral density, mammographic breast density and serum estrogen concentration level? Study on Malaysian women. In 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences - ICIBEL 2017 in conjunction with APCMBE 2017. Vol. 67. Springer Verlag. 2018. p. 259-263 https://doi.org/10.1007/978-981-10-7554-4_45
Zain, N. M. ; Chelliah, Kanaga Kumari ; Latif, Elda Surhaida ; Shantini, A. / Is there a relationship between bone mineral density, mammographic breast density and serum estrogen concentration level? Study on Malaysian women. 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences - ICIBEL 2017 in conjunction with APCMBE 2017. Vol. 67 Springer Verlag, 2018. pp. 259-263
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