Irritable bowel syndrome and inflammatory bowel disease overlap syndrome

Pieces of the puzzle are falling into place

Rafiz Abdul Rani, Raja Affendi Raja Ali, Yeong Yeh Lee

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiology, and treatment, suggesting the possibility of IBS and IBD being a single disease entity albeit at opposite ends of the spectrum. We examined the similarities and differences in IBS and IBD, and offer new thoughts and approaches to the disease paradigm.

Original languageEnglish
Pages (from-to)297-304
Number of pages8
JournalIntestinal Research
Volume14
Issue number4
DOIs
Publication statusPublished - 2016

Fingerprint

Irritable Bowel Syndrome
Inflammatory Bowel Diseases
Incidence
Brain
Therapeutics

Keywords

  • Gut-brain axis
  • IBS-IBD overlap syndrome
  • Inflammatory bowel disease
  • Irritable bowel syndrome

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Irritable bowel syndrome and inflammatory bowel disease overlap syndrome : Pieces of the puzzle are falling into place. / Rani, Rafiz Abdul; Raja Ali, Raja Affendi; Lee, Yeong Yeh.

In: Intestinal Research, Vol. 14, No. 4, 2016, p. 297-304.

Research output: Contribution to journalReview article

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