Irreversible visual loss and optic nerve dysfunction associated with central retinal vein occlusion in waldenstrom macroglobulinemia

S Fadilah S. Abdul Wahid, M. Muhaya, Azlin Ithnin, Fadilah S Abdul Wahid

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Irreversible optic nerve dysfunction associated with central retinal vein occlusion (CRVO) is an unusual but important complication of Waldenstrom Macroglobulinemia (WM). Acute visual loss in CRVO is mainly due the severe macular oedema. However, ischaemic optic neuropathy needs to be considered in patients with CRVO when, (i) there is a relative afferent papillary defect and central scotoma, (ii) the visual acuity is not consistent with the retinal pathology, and (iii) the visual defects persisted despite resolution of macular oedema following treatment of the hyperviscosity state. The ischaemic type of CRVO is associated with a poor visual prognosis and the presenting visual acuity has a prognostic role. We report the first description of irreversible unilateral optic nerve damage associated with CRVO in a patient with WM.

Original languageEnglish
Pages (from-to)349-351
Number of pages3
JournalMedical Journal of Malaysia
Volume62
Issue number4
Publication statusPublished - Oct 2007

Fingerprint

Retinal Vein
Waldenstrom Macroglobulinemia
Retinal Vein Occlusion
Optic Nerve
Macular Edema
Visual Acuity
Ischemic Optic Neuropathy
Scotoma
Pathology

Keywords

  • Central retinal vein occlusion
  • Hyperviscosity
  • Optic nerve
  • Visual loss
  • Waldenstrom's macroglobulinaemia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Irreversible visual loss and optic nerve dysfunction associated with central retinal vein occlusion in waldenstrom macroglobulinemia. / S. Abdul Wahid, S Fadilah; Muhaya, M.; Ithnin, Azlin; Wahid, Fadilah S Abdul.

In: Medical Journal of Malaysia, Vol. 62, No. 4, 10.2007, p. 349-351.

Research output: Contribution to journalArticle

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