Abstract
Background: This study was conducted to determine if intravenous dexamethasone combined with caudal block was able to prolong post-operative analgesia in pediatric daycare surgeries. Methods: Sixty four ASA I or II children aged 3 to 10 year old scheduled for daycare open unilateral herniotomy received general anesthesia and caudal block using 0.25% levobupivacaine 0.75 mg.kg<sup>-1</sup> with suppository paracetamol 30 mg.kg<sup>-1</sup>. After anesthesia induction, they were randomized to receive either intravenous dexamethasone 0.5 mg.kg<sup>-1</sup> (Group I) or same volume intravenous normal saline (Group II). Postoperatively, pain scores were assessed using WongBaker faces scale. At home, their parents assessed and recorded the pain scores, time to first oral paracetamol served and frequency of paracetamol given in two consecutive days post surgery. On the third postoperative day, these information were gathered from the parents via a phone call. Results: There were statistically significant differences between Group I and Group II in the median time to first paracetamol (800 vs 520 min, p = 0.01), mean pain scores postoperative day 1 (1.9 ± 2.0 vs 3.5 ± 2.2, p = 0.05), mean pain score postoperative day 2 (0.8 ± 1.6 vs 2.3 ± 2.0, p = 0.03) and mean frequencies of paracetamol given on postoperative day 2 (0.3 ± 0.8 vs 1.1 ± 1.0, p = 0.02). Conclusion: A single intravenous dexamethasone dose when combined with caudal block reduces postoperative pain, decreases paracetamol requirement and prolongs analgesic duration in children after open herniotomy.
| Original language | English |
|---|---|
| Pages (from-to) | 177-183 |
| Number of pages | 7 |
| Journal | Middle East Journal of Anesthesiology |
| Volume | 23 |
| Issue number | 2 |
| Publication status | Published - 1 Jun 2015 |
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Keywords
- Analgesia
- Daycare
- Dexamethasone
- Pediatric
- Postoperative
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
Intravenous dexamethasone in combination with caudal block prolongs postoperative analgesia in pediatric daycare surgery. / Arbi, Murni Sari Ahmad; Izaham, Azarinah; Kamaruzaman, Esa; Zainuddin, Khairulamir; Ismail, Hamidah; Abdul Manap, Norsidah.
In: Middle East Journal of Anesthesiology, Vol. 23, No. 2, 01.06.2015, p. 177-183.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intravenous dexamethasone in combination with caudal block prolongs postoperative analgesia in pediatric daycare surgery
AU - Arbi, Murni Sari Ahmad
AU - Izaham, Azarinah
AU - Kamaruzaman, Esa
AU - Zainuddin, Khairulamir
AU - Ismail, Hamidah
AU - Abdul Manap, Norsidah
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Background: This study was conducted to determine if intravenous dexamethasone combined with caudal block was able to prolong post-operative analgesia in pediatric daycare surgeries. Methods: Sixty four ASA I or II children aged 3 to 10 year old scheduled for daycare open unilateral herniotomy received general anesthesia and caudal block using 0.25% levobupivacaine 0.75 mg.kg-1 with suppository paracetamol 30 mg.kg-1. After anesthesia induction, they were randomized to receive either intravenous dexamethasone 0.5 mg.kg-1 (Group I) or same volume intravenous normal saline (Group II). Postoperatively, pain scores were assessed using WongBaker faces scale. At home, their parents assessed and recorded the pain scores, time to first oral paracetamol served and frequency of paracetamol given in two consecutive days post surgery. On the third postoperative day, these information were gathered from the parents via a phone call. Results: There were statistically significant differences between Group I and Group II in the median time to first paracetamol (800 vs 520 min, p = 0.01), mean pain scores postoperative day 1 (1.9 ± 2.0 vs 3.5 ± 2.2, p = 0.05), mean pain score postoperative day 2 (0.8 ± 1.6 vs 2.3 ± 2.0, p = 0.03) and mean frequencies of paracetamol given on postoperative day 2 (0.3 ± 0.8 vs 1.1 ± 1.0, p = 0.02). Conclusion: A single intravenous dexamethasone dose when combined with caudal block reduces postoperative pain, decreases paracetamol requirement and prolongs analgesic duration in children after open herniotomy.
AB - Background: This study was conducted to determine if intravenous dexamethasone combined with caudal block was able to prolong post-operative analgesia in pediatric daycare surgeries. Methods: Sixty four ASA I or II children aged 3 to 10 year old scheduled for daycare open unilateral herniotomy received general anesthesia and caudal block using 0.25% levobupivacaine 0.75 mg.kg-1 with suppository paracetamol 30 mg.kg-1. After anesthesia induction, they were randomized to receive either intravenous dexamethasone 0.5 mg.kg-1 (Group I) or same volume intravenous normal saline (Group II). Postoperatively, pain scores were assessed using WongBaker faces scale. At home, their parents assessed and recorded the pain scores, time to first oral paracetamol served and frequency of paracetamol given in two consecutive days post surgery. On the third postoperative day, these information were gathered from the parents via a phone call. Results: There were statistically significant differences between Group I and Group II in the median time to first paracetamol (800 vs 520 min, p = 0.01), mean pain scores postoperative day 1 (1.9 ± 2.0 vs 3.5 ± 2.2, p = 0.05), mean pain score postoperative day 2 (0.8 ± 1.6 vs 2.3 ± 2.0, p = 0.03) and mean frequencies of paracetamol given on postoperative day 2 (0.3 ± 0.8 vs 1.1 ± 1.0, p = 0.02). Conclusion: A single intravenous dexamethasone dose when combined with caudal block reduces postoperative pain, decreases paracetamol requirement and prolongs analgesic duration in children after open herniotomy.
KW - Analgesia
KW - Daycare
KW - Dexamethasone
KW - Pediatric
KW - Postoperative
UR - http://www.scopus.com/inward/record.url?scp=84939541980&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84939541980&partnerID=8YFLogxK
M3 - Article
C2 - 26442394
AN - SCOPUS:84939541980
VL - 23
SP - 177
EP - 183
JO - Middle East Journal of Anesthesiology
JF - Middle East Journal of Anesthesiology
SN - 0544-0440
IS - 2
ER -