Intra-operative frozen sections for ovarian tumors - A tertiary center experience

Nur Zaiti Md Arshad, Beng Kwang Ng, Noor Asmaliza Md Paiman, Zaleha Abdullah Mahdy, Rushdan Mohd Noor

Research output: Contribution to journalArticle

Abstract

Background: Accuracy of diagnosis with intra-operative frozen sections is extremely important in the evaluation of ovarian tumors so that appropriate surgical procedures can be selected. Study design: All patients who with intra-operative frozen sections for ovarian masses in a tertiary center over nine years from June 2008 until April 2017 were reviewed. Frozen section diagnosis and final histopathological reports were compared. Main outcome measures: Sensitivity, specificity, positive and negative predictive values of intra-operative frozen section as compared to final histopathological results for ovarian tumors. Results: A total of 92 cases were recruited for final evaluation. The frozen section diagnoses were comparable with the final histopathological reports in 83.7% of cases. The sensitivity, specificity, positive predictive value and negative predictive value for benign and malignant ovarian tumors were 95.6%, 85.1%, 86.0% and 95.2% and 69.2%, 100%, 100% and 89.2% respectively. For borderline ovarian tumors, the sensitivity and specificity were 76.2% and 88.7%, respectively; the positive predictive value was 66.7% and the negative predictive value was 92.7%. Conclusion: The accuracy of intra-operative frozen section diagnoses for ovarian tumors is high and this approach remains a reliable option in assessing ovarian masses intra-operatively.

Original languageEnglish
Pages (from-to)213-218
Number of pages6
JournalAsian Pacific Journal of Cancer Prevention
Volume19
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018

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Frozen Sections
Neoplasms
Sensitivity and Specificity
Outcome Assessment (Health Care)

Keywords

  • Accuracy
  • Frozen sections
  • Malaysia
  • Ovarian tumors

ASJC Scopus subject areas

  • Epidemiology
  • Oncology
  • Public Health, Environmental and Occupational Health
  • Cancer Research

Cite this

Intra-operative frozen sections for ovarian tumors - A tertiary center experience. / Arshad, Nur Zaiti Md; Ng, Beng Kwang; Paiman, Noor Asmaliza Md; Abdullah Mahdy, Zaleha; Noor, Rushdan Mohd.

In: Asian Pacific Journal of Cancer Prevention, Vol. 19, No. 1, 01.01.2018, p. 213-218.

Research output: Contribution to journalArticle

Arshad, Nur Zaiti Md ; Ng, Beng Kwang ; Paiman, Noor Asmaliza Md ; Abdullah Mahdy, Zaleha ; Noor, Rushdan Mohd. / Intra-operative frozen sections for ovarian tumors - A tertiary center experience. In: Asian Pacific Journal of Cancer Prevention. 2018 ; Vol. 19, No. 1. pp. 213-218.
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