Influenza and respiratory syncytial viral infections in Malaysia: Demographic and clinical perspective

Md. Mostafizur Rahman, Wong Kon Ken, Alfizah Hanafiah, I. Isahak

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: Respiratory infections represent a major public health problem worldwide. The study aimed to determine the prevalence of respiratory syncytial and influenza virus infections and analyzed in respect to demography and clinical perspective. Methods: The specimens were processed by cell culture and immunofluorescent assay (IFA) and real-time reverse transcriptase-PCR (rRT-PCR) for detection of respiratory viruses.  Results: Out of 505 specimens 189 (37.8%) were positive, in which RSV was positive in 124(24.8%) cases and influenza A was positive in 65(13%) cases. Positive cases for influenza virus A and RSV were analyzed based on demography: age, gender, ethnicity and clinical symptoms. There were no significant differences among gender, ethnicity and clinical symptoms in both RSV and influenza A virus infections. It was observed that children below 3 years of ages were more prone to RSV infections. On the contrary, influenza virus A infected all age groups of humans. Conclusion: RSV infects mostly child below 3 years of age and influenza virus infects all age group. No specificity of RSV and influenza infection in relation to demography.

Original languageEnglish
Pages (from-to)161-165
Number of pages5
JournalPakistan Journal of Medical Sciences
Volume30
Issue number1
DOIs
Publication statusPublished - 2014

Fingerprint

Malaysia
Influenza A virus
Virus Diseases
Human Influenza
Demography
Orthomyxoviridae
Age Groups
Respiratory Syncytial Virus Infections
Infection
Reverse Transcriptase Polymerase Chain Reaction
Respiratory Tract Infections
Real-Time Polymerase Chain Reaction
Public Health
Cell Culture Techniques
Viruses

Keywords

  • Demography
  • Immuno Fluorescence Technique
  • Influenza virus
  • Prevalence
  • Real-time reverse transcriptase-PCR
  • Respiratory syncytial virus

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Influenza and respiratory syncytial viral infections in Malaysia : Demographic and clinical perspective. / Rahman, Md. Mostafizur; Kon Ken, Wong; Hanafiah, Alfizah; Isahak, I.

In: Pakistan Journal of Medical Sciences, Vol. 30, No. 1, 2014, p. 161-165.

Research output: Contribution to journalArticle

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