Abstract
Objective: Respiratory infections represent a major public health problem worldwide. The study aimed to determine the prevalence of respiratory syncytial and influenza virus infections and analyzed in respect to demography and clinical perspective. Methods: The specimens were processed by cell culture and immunofluorescent assay (IFA) and real-time reverse transcriptase-PCR (rRT-PCR) for detection of respiratory viruses. Results: Out of 505 specimens 189 (37.8%) were positive, in which RSV was positive in 124(24.8%) cases and influenza A was positive in 65(13%) cases. Positive cases for influenza virus A and RSV were analyzed based on demography: age, gender, ethnicity and clinical symptoms. There were no significant differences among gender, ethnicity and clinical symptoms in both RSV and influenza A virus infections. It was observed that children below 3 years of ages were more prone to RSV infections. On the contrary, influenza virus A infected all age groups of humans. Conclusion: RSV infects mostly child below 3 years of age and influenza virus infects all age group. No specificity of RSV and influenza infection in relation to demography.
| Original language | English |
|---|---|
| Pages (from-to) | 161-165 |
| Number of pages | 5 |
| Journal | Pakistan Journal of Medical Sciences |
| Volume | 30 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2014 |
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Keywords
- Demography
- Immuno Fluorescence Technique
- Influenza virus
- Prevalence
- Real-time reverse transcriptase-PCR
- Respiratory syncytial virus
ASJC Scopus subject areas
- Medicine(all)
Cite this
Influenza and respiratory syncytial viral infections in Malaysia : Demographic and clinical perspective. / Rahman, Md. Mostafizur; Kon Ken, Wong; Hanafiah, Alfizah; Isahak, I.
In: Pakistan Journal of Medical Sciences, Vol. 30, No. 1, 2014, p. 161-165.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Influenza and respiratory syncytial viral infections in Malaysia
T2 - Demographic and clinical perspective
AU - Rahman, Md. Mostafizur
AU - Kon Ken, Wong
AU - Hanafiah, Alfizah
AU - Isahak, I.
PY - 2014
Y1 - 2014
N2 - Objective: Respiratory infections represent a major public health problem worldwide. The study aimed to determine the prevalence of respiratory syncytial and influenza virus infections and analyzed in respect to demography and clinical perspective. Methods: The specimens were processed by cell culture and immunofluorescent assay (IFA) and real-time reverse transcriptase-PCR (rRT-PCR) for detection of respiratory viruses. Results: Out of 505 specimens 189 (37.8%) were positive, in which RSV was positive in 124(24.8%) cases and influenza A was positive in 65(13%) cases. Positive cases for influenza virus A and RSV were analyzed based on demography: age, gender, ethnicity and clinical symptoms. There were no significant differences among gender, ethnicity and clinical symptoms in both RSV and influenza A virus infections. It was observed that children below 3 years of ages were more prone to RSV infections. On the contrary, influenza virus A infected all age groups of humans. Conclusion: RSV infects mostly child below 3 years of age and influenza virus infects all age group. No specificity of RSV and influenza infection in relation to demography.
AB - Objective: Respiratory infections represent a major public health problem worldwide. The study aimed to determine the prevalence of respiratory syncytial and influenza virus infections and analyzed in respect to demography and clinical perspective. Methods: The specimens were processed by cell culture and immunofluorescent assay (IFA) and real-time reverse transcriptase-PCR (rRT-PCR) for detection of respiratory viruses. Results: Out of 505 specimens 189 (37.8%) were positive, in which RSV was positive in 124(24.8%) cases and influenza A was positive in 65(13%) cases. Positive cases for influenza virus A and RSV were analyzed based on demography: age, gender, ethnicity and clinical symptoms. There were no significant differences among gender, ethnicity and clinical symptoms in both RSV and influenza A virus infections. It was observed that children below 3 years of ages were more prone to RSV infections. On the contrary, influenza virus A infected all age groups of humans. Conclusion: RSV infects mostly child below 3 years of age and influenza virus infects all age group. No specificity of RSV and influenza infection in relation to demography.
KW - Demography
KW - Immuno Fluorescence Technique
KW - Influenza virus
KW - Prevalence
KW - Real-time reverse transcriptase-PCR
KW - Respiratory syncytial virus
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U2 - 10.12669/pjms.301.4272
DO - 10.12669/pjms.301.4272
M3 - Article
VL - 30
SP - 161
EP - 165
JO - Pakistan Journal of Medical Sciences
JF - Pakistan Journal of Medical Sciences
SN - 1682-024X
IS - 1
ER -