In vivo irritation study of Melastoma malabathricum cream formulation on ICR mice

Rabiahtul Adarwiyah Mohd Yasin, Khairunadwa Jemon, Norefrina Shafinaz Md Nor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Melastoma malabathricum is a traditional herb that is used to treat wound on skin. It has also been proven to have antiviral activity against Herpes Simplex virus type 1 (HSV-1). In this study, M. malabathricum cream formulation was developed by incorporating M. malabathricum aqueous extract into cream base. The safety and biocompatibility of the formulated cream was investigated by topically applying the cream onto the back of ICR mice skin. Treatment with M. malabathricum was found to accelerate wound contraction with less scar formation. The effect of M. malabathricum has prompted a possibility that M. malabathricum might contribute in enhancing the healing process of cutaneous lesion caused by HSV-1. The formulated cream did not cause any skin irritation or adverse effect to ICR mice when topically applied within seven days of exposure.

Original languageEnglish
Title of host publication2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium
PublisherAmerican Institute of Physics Inc.
Volume1784
ISBN (Electronic)9780735414464
DOIs
Publication statusPublished - 17 Nov 2016
Event2016 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2016 - Selangor, Malaysia
Duration: 13 Apr 201614 Apr 2016

Other

Other2016 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2016
CountryMalaysia
CitySelangor
Period13/4/1614/4/16

Fingerprint

irritation
viruses
mice
formulations
scars
healing
biocompatibility
lesions
contraction
safety
causes

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Yasin, R. A. M., Jemon, K., & Md Nor, N. S. (2016). In vivo irritation study of Melastoma malabathricum cream formulation on ICR mice. In 2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium (Vol. 1784). [020026] American Institute of Physics Inc.. https://doi.org/10.1063/1.4966736

In vivo irritation study of Melastoma malabathricum cream formulation on ICR mice. / Yasin, Rabiahtul Adarwiyah Mohd; Jemon, Khairunadwa; Md Nor, Norefrina Shafinaz.

2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. Vol. 1784 American Institute of Physics Inc., 2016. 020026.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yasin, RAM, Jemon, K & Md Nor, NS 2016, In vivo irritation study of Melastoma malabathricum cream formulation on ICR mice. in 2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. vol. 1784, 020026, American Institute of Physics Inc., 2016 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2016, Selangor, Malaysia, 13/4/16. https://doi.org/10.1063/1.4966736
Yasin RAM, Jemon K, Md Nor NS. In vivo irritation study of Melastoma malabathricum cream formulation on ICR mice. In 2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. Vol. 1784. American Institute of Physics Inc. 2016. 020026 https://doi.org/10.1063/1.4966736
Yasin, Rabiahtul Adarwiyah Mohd ; Jemon, Khairunadwa ; Md Nor, Norefrina Shafinaz. / In vivo irritation study of Melastoma malabathricum cream formulation on ICR mice. 2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. Vol. 1784 American Institute of Physics Inc., 2016.
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