Hydroxypropylcellulose as a novel green reservoir for the synthesis, stabilization, and storage of silver nanoparticles

Muhammad Ajaz Hussain, Abdullah Shah, Ibrahim Jantan, Muhammad Raza Shah, Muhammad Nawaz Tahir, Riaz Ahmad, Bukhari Syed Nasir Abbas

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Polysaccharides are attracting the vigil eye of researchers in order to design the green synthesis of silver nanoparticles (Ag NPs) of diverse size, shape, and application. We report an environmentally friendly method to synthesize Ag NPs where no physical reaction conditions were employed. Hydroxypropylcellulose (HPC) was used as a template nanoreactor, stabilizer, and capping agent to obtain Ag NPs. Different concentrations of AgNO<inf>3</inf> solutions (50 mmol, 75 mmol, and 100 mmol) were mixed with a concentrated aqueous solution of HPC and the progress of the reaction was monitored by noting color changes of the reaction mixture at different reaction times for up to 24 hours. Characteristic ultraviolet–visible spectroscopy (UV/Vis) absorption bands of Ag NPs were observed in the range of 388–452 nm. The morphology of the Ag NPs was studied by scanning electron microscopy, transmission electron microscopy (TEM), and atomic force microscopy. The TEM images confirmed that the size of the Ag NPs was in the range of 25–55 nm. Powder X-ray diffraction studies showed that the crystal phase of the Ag NPs was face-centered cubic. The as-prepared Ag NPs were found to be stable, and no changes in size and morphology were observed after storage in HPC thin films over 1 year, as indicated by UV/Vis spectra. So, the present work furnishes a green and economical strategy for the synthesis and storage of stable Ag NPs. As-synthesized Ag NPs showed significant antimicrobial activity against different bacterial (Escherichia coli, Staphylococcus epidermidis, S. aureus, Bacillus subtilis, Pseudomonas aeruginosa) and fungal strains (Actinomycetes and Aspergillus niger).

Original languageEnglish
Pages (from-to)2079-2088
Number of pages10
JournalInternational Journal of Nanomedicine
Volume10
DOIs
Publication statusPublished - 16 Mar 2015

Fingerprint

Silver
Nanoparticles
Stabilization
Nanoreactors
Spectroscopy
Transmission electron microscopy
Transmission Electron Microscopy
Stabilizers (agents)
Aspergillus
Spectrum Analysis
Bacilli
Polysaccharides
X ray powder diffraction
Escherichia coli
Absorption spectra
Atomic force microscopy
Staphylococcus epidermidis
Aspergillus niger
Actinobacteria
Atomic Force Microscopy

Keywords

  • Antimicrobial assay
  • Green synthesis
  • Nanobiotechnology
  • Nanoreactor
  • Stability
  • Storage

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Organic Chemistry
  • Drug Discovery

Cite this

Hydroxypropylcellulose as a novel green reservoir for the synthesis, stabilization, and storage of silver nanoparticles. / Hussain, Muhammad Ajaz; Shah, Abdullah; Jantan, Ibrahim; Shah, Muhammad Raza; Tahir, Muhammad Nawaz; Ahmad, Riaz; Syed Nasir Abbas, Bukhari.

In: International Journal of Nanomedicine, Vol. 10, 16.03.2015, p. 2079-2088.

Research output: Contribution to journalArticle

Hussain, Muhammad Ajaz ; Shah, Abdullah ; Jantan, Ibrahim ; Shah, Muhammad Raza ; Tahir, Muhammad Nawaz ; Ahmad, Riaz ; Syed Nasir Abbas, Bukhari. / Hydroxypropylcellulose as a novel green reservoir for the synthesis, stabilization, and storage of silver nanoparticles. In: International Journal of Nanomedicine. 2015 ; Vol. 10. pp. 2079-2088.
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