Human respiratory epithelial cells from nasal turbinate expressed stem cell genes even after serial passaging

B. H I Ruszymah, B. A. Azrul Izham, M. Y. Mohd Heikal, S. F. Khor, M. B. Fauzi, B. S. Aminuddin

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Current development in the field of tissue engineering led to the idea of repairing and regenerating the respiratory airway through in vitro reconstruction using autologous respiratory epithelial (RE). To ensure the capability of proliferation, the stem cell property of RE cells from the nasal turbinate should be evaluated. Respiratory epithelial cells from six human nasal turbinates were harvested and cultured in vitro. The gene expression of FZD-9 and BST-1 were expressed in passage 2 (P2) and passage 4 (P4). The levels of expression were not significant between both passages. The RE cells exhibit the stem cell properties, which remains even after serial passaging.

Original languageEnglish
Pages (from-to)440-442
Number of pages3
JournalMedical Journal of Malaysia
Volume66
Issue number5
Publication statusPublished - Dec 2011

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Turbinates
Nose
Stem Cells
Epithelial Cells
Genes
Tissue Engineering
Gene Expression
In Vitro Techniques

Keywords

  • Gene expression analysis
  • Human respiratory epithelial cells
  • Nasal turbinate
  • Stem cell marker
  • Tissue engineering

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Human respiratory epithelial cells from nasal turbinate expressed stem cell genes even after serial passaging. / Ruszymah, B. H I; Azrul Izham, B. A.; Mohd Heikal, M. Y.; Khor, S. F.; Fauzi, M. B.; Aminuddin, B. S.

In: Medical Journal of Malaysia, Vol. 66, No. 5, 12.2011, p. 440-442.

Research output: Contribution to journalArticle

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