HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 194 Southeast Asia Chinese from Peninsular Malaysia

Chun Lai Too, Lay Kim Tan, Hussein Heselynn, Shahril Nor-Shuhaila, Mageswaran Eashwary, Sulaiman Wahinuddin, Ing Soo Lau, Suk Chyn Gun, Mohamed Said Mohd-Shahrir, Mohd Mokhtar Ainon, Rosman Azmillah, Othman Muhaini, Murad Shahnaz

Research output: Contribution to journalArticle

Abstract

A total of 194 Southeast Asia Chinese from Peninsular Malaysia were genotyped for HLA-A, -B, -C -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, the HLA-B, HLA-DRB1 and HLA-DQB1 were in Hardy-Weinberg proportions (HWEP) (p > 0.05). We observed significant deviation from HWEP in HLA-A (p < 0.05) and HLA-C (p < 0.01) loci. This genotype data was available in Allele Frequencies Network Database (AFND) Dos Santos et al. (2016).

Original languageEnglish
Pages (from-to)906-907
Number of pages2
JournalHuman Immunology
Volume80
Issue number11
DOIs
Publication statusPublished - Nov 2019

Fingerprint

Southeastern Asia
HLA-A Antigens
HLA-B Antigens
Malaysia
Haplotypes
Alleles
HLA-C Antigens
HLA-DRB1 Chains
Oligonucleotide Probes
Gene Frequency
Genotype
Databases
Polymerase Chain Reaction
HLA-DQB1 antigen

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Too, C. L., Tan, L. K., Heselynn, H., Nor-Shuhaila, S., Eashwary, M., Wahinuddin, S., ... Shahnaz, M. (2019). HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 194 Southeast Asia Chinese from Peninsular Malaysia. Human Immunology, 80(11), 906-907. https://doi.org/10.1016/j.humimm.2019.09.005

HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 194 Southeast Asia Chinese from Peninsular Malaysia. / Too, Chun Lai; Tan, Lay Kim; Heselynn, Hussein; Nor-Shuhaila, Shahril; Eashwary, Mageswaran; Wahinuddin, Sulaiman; Lau, Ing Soo; Gun, Suk Chyn; Mohd-Shahrir, Mohamed Said; Ainon, Mohd Mokhtar; Azmillah, Rosman; Muhaini, Othman; Shahnaz, Murad.

In: Human Immunology, Vol. 80, No. 11, 11.2019, p. 906-907.

Research output: Contribution to journalArticle

Too, CL, Tan, LK, Heselynn, H, Nor-Shuhaila, S, Eashwary, M, Wahinuddin, S, Lau, IS, Gun, SC, Mohd-Shahrir, MS, Ainon, MM, Azmillah, R, Muhaini, O & Shahnaz, M 2019, 'HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 194 Southeast Asia Chinese from Peninsular Malaysia', Human Immunology, vol. 80, no. 11, pp. 906-907. https://doi.org/10.1016/j.humimm.2019.09.005
Too, Chun Lai ; Tan, Lay Kim ; Heselynn, Hussein ; Nor-Shuhaila, Shahril ; Eashwary, Mageswaran ; Wahinuddin, Sulaiman ; Lau, Ing Soo ; Gun, Suk Chyn ; Mohd-Shahrir, Mohamed Said ; Ainon, Mohd Mokhtar ; Azmillah, Rosman ; Muhaini, Othman ; Shahnaz, Murad. / HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 194 Southeast Asia Chinese from Peninsular Malaysia. In: Human Immunology. 2019 ; Vol. 80, No. 11. pp. 906-907.
@article{45f34ec97ab646c5b5e9208edf1695e4,
title = "HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 194 Southeast Asia Chinese from Peninsular Malaysia",
abstract = "A total of 194 Southeast Asia Chinese from Peninsular Malaysia were genotyped for HLA-A, -B, -C -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, the HLA-B, HLA-DRB1 and HLA-DQB1 were in Hardy-Weinberg proportions (HWEP) (p > 0.05). We observed significant deviation from HWEP in HLA-A (p < 0.05) and HLA-C (p < 0.01) loci. This genotype data was available in Allele Frequencies Network Database (AFND) Dos Santos et al. (2016).",
author = "Too, {Chun Lai} and Tan, {Lay Kim} and Hussein Heselynn and Shahril Nor-Shuhaila and Mageswaran Eashwary and Sulaiman Wahinuddin and Lau, {Ing Soo} and Gun, {Suk Chyn} and Mohd-Shahrir, {Mohamed Said} and Ainon, {Mohd Mokhtar} and Rosman Azmillah and Othman Muhaini and Murad Shahnaz",
year = "2019",
month = "11",
doi = "10.1016/j.humimm.2019.09.005",
language = "English",
volume = "80",
pages = "906--907",
journal = "Human Immunology",
issn = "0198-8859",
publisher = "Elsevier Inc.",
number = "11",

}

TY - JOUR

T1 - HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 194 Southeast Asia Chinese from Peninsular Malaysia

AU - Too, Chun Lai

AU - Tan, Lay Kim

AU - Heselynn, Hussein

AU - Nor-Shuhaila, Shahril

AU - Eashwary, Mageswaran

AU - Wahinuddin, Sulaiman

AU - Lau, Ing Soo

AU - Gun, Suk Chyn

AU - Mohd-Shahrir, Mohamed Said

AU - Ainon, Mohd Mokhtar

AU - Azmillah, Rosman

AU - Muhaini, Othman

AU - Shahnaz, Murad

PY - 2019/11

Y1 - 2019/11

N2 - A total of 194 Southeast Asia Chinese from Peninsular Malaysia were genotyped for HLA-A, -B, -C -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, the HLA-B, HLA-DRB1 and HLA-DQB1 were in Hardy-Weinberg proportions (HWEP) (p > 0.05). We observed significant deviation from HWEP in HLA-A (p < 0.05) and HLA-C (p < 0.01) loci. This genotype data was available in Allele Frequencies Network Database (AFND) Dos Santos et al. (2016).

AB - A total of 194 Southeast Asia Chinese from Peninsular Malaysia were genotyped for HLA-A, -B, -C -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, the HLA-B, HLA-DRB1 and HLA-DQB1 were in Hardy-Weinberg proportions (HWEP) (p > 0.05). We observed significant deviation from HWEP in HLA-A (p < 0.05) and HLA-C (p < 0.01) loci. This genotype data was available in Allele Frequencies Network Database (AFND) Dos Santos et al. (2016).

UR - http://www.scopus.com/inward/record.url?scp=85072538710&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85072538710&partnerID=8YFLogxK

U2 - 10.1016/j.humimm.2019.09.005

DO - 10.1016/j.humimm.2019.09.005

M3 - Article

C2 - 31558331

AN - SCOPUS:85072538710

VL - 80

SP - 906

EP - 907

JO - Human Immunology

JF - Human Immunology

SN - 0198-8859

IS - 11

ER -