Abstract
Background & Objectives: The burden of stroke is increasing, in part due to increasing prevalence of diabetes mellitus. Given the high prevalence of diabetes in the Malaysian population (22.6%), we aimed to determine the prevalence of diabetes in our stroke population. We also aimed to study the stroke subtype associated with diabetes. We hypothesized that lacunar infarction would be more prevalent in diabetics. Methods: We retrospectively reviewed data of consecutive patients with acute ischaemic stroke admitted from October 2004 to December 2010 from our stroke registry. Demographic data, risk factors profile and stroke subtypes were reviewed and analyzed. Results: Eight hundred and fifty eight patients were identified from the registry. As high as 59.3% (n=509) of our patients were diabetics, of which 49.2% (n=422) had pre-existing diabetes and 10.1% (n=87) were newly diagnosed. Lacunar infarction was the commonest stroke subtype, comprising 60.6% (n=519) of all strokes. Diabetes was significantly associated with lacunar infarction (OR 1.5, CI 95% 1.16-2.01, p=0.003), particularly in those aged < 55 years (OR 2.29, 95% CI 1.12-4.67) and HbA1C > 6.5% (x<sup>2</sup>=8.77, p=0.003). Conclusions: The prevalence of diabetes in our stroke patients is amongst the highest reported. Diabetes mellitus, particularly those with poor glycaemic control is strongly associated with lacunar infarction.
| Original language | English |
|---|---|
| Pages (from-to) | 121-127 |
| Number of pages | 7 |
| Journal | Neurology Asia |
| Volume | 20 |
| Issue number | 2 |
| Publication status | Published - 1 Jun 2015 |
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ASJC Scopus subject areas
- Clinical Neurology
- Neurology
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High prevalence of diabetes in stroke patients and its association with lacunar infarction. / Law, Zhe Kang; Wan Yahya, Wan Nur Nafisah; Sahathevan, Ramesh; Hing, Jee Yong; Zakaria, Mohd Firdaus; Mohd Shuhari, Nurul Munirah; Ahmad, Nur Fathihah; Ting, Teong Kui; Tan, Hui Jan; Md. Rani, Shahrul Azmin; Remli, Rabani; Mohammed Nawi, Azmawati; Mohamed Ibrahim, Norlinah.
In: Neurology Asia, Vol. 20, No. 2, 01.06.2015, p. 121-127.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - High prevalence of diabetes in stroke patients and its association with lacunar infarction
AU - Law, Zhe Kang
AU - Wan Yahya, Wan Nur Nafisah
AU - Sahathevan, Ramesh
AU - Hing, Jee Yong
AU - Zakaria, Mohd Firdaus
AU - Mohd Shuhari, Nurul Munirah
AU - Ahmad, Nur Fathihah
AU - Ting, Teong Kui
AU - Tan, Hui Jan
AU - Md. Rani, Shahrul Azmin
AU - Remli, Rabani
AU - Mohammed Nawi, Azmawati
AU - Mohamed Ibrahim, Norlinah
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Background & Objectives: The burden of stroke is increasing, in part due to increasing prevalence of diabetes mellitus. Given the high prevalence of diabetes in the Malaysian population (22.6%), we aimed to determine the prevalence of diabetes in our stroke population. We also aimed to study the stroke subtype associated with diabetes. We hypothesized that lacunar infarction would be more prevalent in diabetics. Methods: We retrospectively reviewed data of consecutive patients with acute ischaemic stroke admitted from October 2004 to December 2010 from our stroke registry. Demographic data, risk factors profile and stroke subtypes were reviewed and analyzed. Results: Eight hundred and fifty eight patients were identified from the registry. As high as 59.3% (n=509) of our patients were diabetics, of which 49.2% (n=422) had pre-existing diabetes and 10.1% (n=87) were newly diagnosed. Lacunar infarction was the commonest stroke subtype, comprising 60.6% (n=519) of all strokes. Diabetes was significantly associated with lacunar infarction (OR 1.5, CI 95% 1.16-2.01, p=0.003), particularly in those aged < 55 years (OR 2.29, 95% CI 1.12-4.67) and HbA1C > 6.5% (x2=8.77, p=0.003). Conclusions: The prevalence of diabetes in our stroke patients is amongst the highest reported. Diabetes mellitus, particularly those with poor glycaemic control is strongly associated with lacunar infarction.
AB - Background & Objectives: The burden of stroke is increasing, in part due to increasing prevalence of diabetes mellitus. Given the high prevalence of diabetes in the Malaysian population (22.6%), we aimed to determine the prevalence of diabetes in our stroke population. We also aimed to study the stroke subtype associated with diabetes. We hypothesized that lacunar infarction would be more prevalent in diabetics. Methods: We retrospectively reviewed data of consecutive patients with acute ischaemic stroke admitted from October 2004 to December 2010 from our stroke registry. Demographic data, risk factors profile and stroke subtypes were reviewed and analyzed. Results: Eight hundred and fifty eight patients were identified from the registry. As high as 59.3% (n=509) of our patients were diabetics, of which 49.2% (n=422) had pre-existing diabetes and 10.1% (n=87) were newly diagnosed. Lacunar infarction was the commonest stroke subtype, comprising 60.6% (n=519) of all strokes. Diabetes was significantly associated with lacunar infarction (OR 1.5, CI 95% 1.16-2.01, p=0.003), particularly in those aged < 55 years (OR 2.29, 95% CI 1.12-4.67) and HbA1C > 6.5% (x2=8.77, p=0.003). Conclusions: The prevalence of diabetes in our stroke patients is amongst the highest reported. Diabetes mellitus, particularly those with poor glycaemic control is strongly associated with lacunar infarction.
UR - http://www.scopus.com/inward/record.url?scp=84934766872&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84934766872&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84934766872
VL - 20
SP - 121
EP - 127
JO - Neurology Asia
JF - Neurology Asia
SN - 1823-6138
IS - 2
ER -