High and Heterogeneous Prevalence of Asymptomatic and Sub-microscopic Malaria Infections on Islands in Lake Victoria, Kenya

Zulkarnain Md Idris, Chim W. Chan, James Kongere, Jesse Gitaka, John Logedi, Ahmeddin Omar, Charles Obonyo, Beatrice Kemunto Machini, Rie Isozumi, Isao Teramoto, Masatsugu Kimura, Akira Kaneko

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Kenya is intensifying its national efforts in malaria control to achieve malaria elimination. Detailed characterization of malaria infection among populations living in the areas where the disease is endemic in Kenya is a crucial priority, especially for planning and evaluating future malaria elimination strategy. This study aimed to investigate the distribution and extent of malaria infection on islands in Lake Victoria of Kenya to aid in designing new interventions for malaria elimination. Five cross-sectional surveys were conducted between January 2012 and August 2014 on four islands (Mfangano, Takawiri, Kibuogi and Ngodhe) in Lake Victoria and a coastal mainland (Ungoye). Malaria prevalence varied significantly among settings: highest in Ungoye, followed by the large island of Mfangano and lowest in the three remaining small islands. Of the 3867 malaria infections detected by PCR, 91.8% were asymptomatic, 50.3% were sub-microscopic, of which 94% were also asymptomatic. We observed geographical differences and age dependency in both proportion of sub-microscopic infections and asymptomatic parasite carriage. Our findings highlighted the local heterogeneity in malaria prevalence on islands and a coastal area in Lake Victoria, and provided support for the inclusion of mass drug administration as a component of the intervention package to eliminate malaria on islands.

Original languageEnglish
Article number36958
JournalScientific Reports
Volume6
DOIs
Publication statusPublished - 14 Nov 2016

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Victoria
Kenya
Lakes
Islands
Malaria
Infection
Endemic Diseases
Parasitic Diseases
Asymptomatic Infections
Cross-Sectional Studies
Polymerase Chain Reaction

ASJC Scopus subject areas

  • General

Cite this

High and Heterogeneous Prevalence of Asymptomatic and Sub-microscopic Malaria Infections on Islands in Lake Victoria, Kenya. / Md Idris, Zulkarnain; Chan, Chim W.; Kongere, James; Gitaka, Jesse; Logedi, John; Omar, Ahmeddin; Obonyo, Charles; Machini, Beatrice Kemunto; Isozumi, Rie; Teramoto, Isao; Kimura, Masatsugu; Kaneko, Akira.

In: Scientific Reports, Vol. 6, 36958, 14.11.2016.

Research output: Contribution to journalArticle

Md Idris, Z, Chan, CW, Kongere, J, Gitaka, J, Logedi, J, Omar, A, Obonyo, C, Machini, BK, Isozumi, R, Teramoto, I, Kimura, M & Kaneko, A 2016, 'High and Heterogeneous Prevalence of Asymptomatic and Sub-microscopic Malaria Infections on Islands in Lake Victoria, Kenya', Scientific Reports, vol. 6, 36958. https://doi.org/10.1038/srep36958
Md Idris, Zulkarnain ; Chan, Chim W. ; Kongere, James ; Gitaka, Jesse ; Logedi, John ; Omar, Ahmeddin ; Obonyo, Charles ; Machini, Beatrice Kemunto ; Isozumi, Rie ; Teramoto, Isao ; Kimura, Masatsugu ; Kaneko, Akira. / High and Heterogeneous Prevalence of Asymptomatic and Sub-microscopic Malaria Infections on Islands in Lake Victoria, Kenya. In: Scientific Reports. 2016 ; Vol. 6.
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