O envolvimento do nervo mediano na artrite reumatoide tem sido excessivamente valorizado?

Translated title of the contribution: Has the median nerve involvement in rheumatoid arthritis been overemphasized?

Research output: Contribution to journalArticle

Abstract

Rheumatoid arthritis (RA) is a well and widely recognised cause of carpal tunnel syndrome (CTS). In the rheumatoid wrist, synovial expansion, joint erosions and ligamentous laxity result in compression of the median nerve due to increased intracarpal pressure. We evaluated the published studies to determine the prevalence of CTS and the characteristics of the median nerve in RA and its association with clinical parameters such as disease activity, disease duration and seropositivity. A total of 13 studies met the eligibility criteria. Pooled data from 8 studies with random selection of RA patients revealed that 86 out of 1561 (5.5%) subjects had CTS. Subclinical CTS, on the other hand, had a pooled prevalence of 14.0% (30/215). The cross sectional area of the median nerve of the RA patients without CTS were similar to the healthy controls. The vast majority of the studies (8/13) disclosed no significant relationship between the median nerve findings and the clinical or laboratory parameters in RA. The link between RA and the median nerve abnormalities has been overemphasized throughout the literature. The prevalence of CTS in RA is similar to the general population without any correlation between the median nerve characteristics and the clinical parameters of RA.

Original languagePortuguese
Pages (from-to)122-128
Number of pages7
JournalRevista Brasileira de Reumatologia
Volume57
Issue number2
DOIs
Publication statusPublished - 1 Mar 2017

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Median Nerve
Carpal Tunnel Syndrome
Rheumatoid Arthritis
Wrist
Joints
Pressure
Population

Keywords

  • Carpal tunnel syndrome
  • Median nerve
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Rheumatology

Cite this

O envolvimento do nervo mediano na artrite reumatoide tem sido excessivamente valorizado? / Rajalingham, Sakthiswary; Singh, Rajesh.

In: Revista Brasileira de Reumatologia, Vol. 57, No. 2, 01.03.2017, p. 122-128.

Research output: Contribution to journalArticle

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