Growth kinetic study on normal and microtic chondrocytes of human auricular cartilage.

M. F. Ishak, B. S. Aminuddin, Asma Abdullah, B. S. Lokman, Ruszymah Idrus, Bee See Goh

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Abstract

Chondrocytes were isolated from normal and microtic human auricular cartilage after ear surgery carried out at Universiti Kebangsaan Malaysia Medical Centre. Chondrocytes were cultured and expanded until passage 4. After reached confluence, cultured chondrocytes at each passage (P1, P2, P3 and P4) were harvested and assigned for growth profile analysis. There was no significant difference in cell viability between both normal and microtic samples (p = 0.84). Both samples showed no significant differences for growth profile parameters in terms of growth rate, population doubling time and total number of cell doubling, except in passage 1, where there is significant difference in cell growth rate (p = 0.004). This preliminary data has indicated that chondrocytes from microtic cartilage has the potential to be used in the reconstruction of human pinna in the future.

Original languageEnglish
Pages (from-to)117-118
Number of pages2
JournalThe Medical journal of Malaysia
Volume63 Suppl A
Publication statusPublished - Jul 2008

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Ear Cartilage
Chondrocytes
Growth
Population Growth
Malaysia
Cartilage
Ear
Cell Survival
Cell Count

ASJC Scopus subject areas

  • Medicine(all)

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Growth kinetic study on normal and microtic chondrocytes of human auricular cartilage. / Ishak, M. F.; Aminuddin, B. S.; Abdullah, Asma; Lokman, B. S.; Idrus, Ruszymah; Goh, Bee See.

In: The Medical journal of Malaysia, Vol. 63 Suppl A, 07.2008, p. 117-118.

Research output: Contribution to journalArticle

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