Graphical interface for gene network inference application

Suhaila Zainudin, Sim Kah Wei, Safaai Deris

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A gene network shows the interactions between genes. Previous research has successfully infer gene network from microar-ray gene expression data using techniques from diverse fields such as pattern detection, machine learning and data mining. In this research, we applied the statistical language R for gene network inference. R provides statistical language and programming environment for statistical computing and graphics. We observed that R only provides command line interface with basic comand buttons. Hence, we built a gene network inference application with Microsoft Visual C# as the visual front-end and R as the back-end for novice R users who are interested to use our gene network inference tool. Th application has tabs which represents each phase of our inference methodology. Each time a user select and click, the command will be executed through the visual interface. Therefore, users no longer need to use the command line. The inference of gene network from gene expression data is useful for predicting relationships between genes. Gene network inference is important because it enhances the understanding on genomic function and directly helps development in bioinformatics and medical field.

Original languageEnglish
Title of host publicationProceedings 2010 International Symposium on Information Technology - Visual Informatics, ITSim'10
Volume1
DOIs
Publication statusPublished - 2010
Event2010 International Symposium on Information Technology, ITSim'10 - Kuala Lumpur
Duration: 15 Jun 201017 Jun 2010

Other

Other2010 International Symposium on Information Technology, ITSim'10
CityKuala Lumpur
Period15/6/1017/6/10

Fingerprint

Genes
Gene expression
Bioinformatics
Data mining
Learning systems

Keywords

  • Gene network
  • Inference
  • Microarray

ASJC Scopus subject areas

  • Computer Networks and Communications
  • Information Systems

Cite this

Zainudin, S., Wei, S. K., & Deris, S. (2010). Graphical interface for gene network inference application. In Proceedings 2010 International Symposium on Information Technology - Visual Informatics, ITSim'10 (Vol. 1). [5561435] https://doi.org/10.1109/ITSIM.2010.5561435

Graphical interface for gene network inference application. / Zainudin, Suhaila; Wei, Sim Kah; Deris, Safaai.

Proceedings 2010 International Symposium on Information Technology - Visual Informatics, ITSim'10. Vol. 1 2010. 5561435.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zainudin, S, Wei, SK & Deris, S 2010, Graphical interface for gene network inference application. in Proceedings 2010 International Symposium on Information Technology - Visual Informatics, ITSim'10. vol. 1, 5561435, 2010 International Symposium on Information Technology, ITSim'10, Kuala Lumpur, 15/6/10. https://doi.org/10.1109/ITSIM.2010.5561435
Zainudin S, Wei SK, Deris S. Graphical interface for gene network inference application. In Proceedings 2010 International Symposium on Information Technology - Visual Informatics, ITSim'10. Vol. 1. 2010. 5561435 https://doi.org/10.1109/ITSIM.2010.5561435
Zainudin, Suhaila ; Wei, Sim Kah ; Deris, Safaai. / Graphical interface for gene network inference application. Proceedings 2010 International Symposium on Information Technology - Visual Informatics, ITSim'10. Vol. 1 2010.
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