Glucuronoxylan-mediated silver nanoparticles

Green synthesis, antimicrobial and wound healing applications

Gulzar Muhammad, Muhammad Ajaz Hussain, Muhammad Amin, Syed Zajif Hussain, Irshad Hussain, Bukhari Syed Nasir Abbas, Muhammad Naeem-Ul-Hassan

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Hydrogel forming polysaccharides are attracting attention for the design of diverse nature silver nanoparticles (Ag NPs) with potential biological applications. Herein, we report the green synthesis of Ag NPs and their antimicrobial activity along with their potential application in wound dressings. Glucuronoxylan (GX) isolated from seeds of Mimosa pudica (MP) was used as a stabilizing/capping agent to prepare the NPs under diffused sunlight using different concentrations of AgNO3. The progress of the reaction was monitored using a UV-visible spectrophotometer and characteristic surface plasmon absorption (SPR) bands were found in the range of 390-465 nm. The morphology and elemental composition of the synthesized Ag NPs were analyzed using scanning electron microscopy equipped with STEM and EDS detectors and the diameter of the Ag NPs was found to be in the range of 2 to 18 nm. The synthesized NPs exhibited antimicrobial potential against Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus, Aspergillus Niger, Penicillium notatum, Rhizopus stolonifer and Actinomycetes odontolyticus. The minimal inhibitory concentrations (MICs) of the Ag NPs against different pathogenic strains were determined. Moreover, the dressing prepared from Ag NP impregnated GX exhibited a remarkable wound healing potential in rabbits. In situ synthesized Ag NPs were stored in the form of GX thin films and their UV/vis spectra exhibited that the texture of the Ag NPs remained intact after a six month storage period.

Original languageEnglish
Pages (from-to)42900-42908
Number of pages9
JournalRSC Advances
Volume7
Issue number68
DOIs
Publication statusPublished - 1 Jan 2017
Externally publishedYes

Fingerprint

Silver
Nanoparticles
Aspergillus
Spectrophotometers
Bacilli
Polysaccharides
Hydrogels
Escherichia coli
Seed
Absorption spectra
Energy dispersive spectroscopy
Textures
Hydrogel
Detectors
Thin films
Scanning electron microscopy
Chemical analysis
glucuronoxylan

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Muhammad, G., Hussain, M. A., Amin, M., Hussain, S. Z., Hussain, I., Syed Nasir Abbas, B., & Naeem-Ul-Hassan, M. (2017). Glucuronoxylan-mediated silver nanoparticles: Green synthesis, antimicrobial and wound healing applications. RSC Advances, 7(68), 42900-42908. https://doi.org/10.1039/c7ra07555c

Glucuronoxylan-mediated silver nanoparticles : Green synthesis, antimicrobial and wound healing applications. / Muhammad, Gulzar; Hussain, Muhammad Ajaz; Amin, Muhammad; Hussain, Syed Zajif; Hussain, Irshad; Syed Nasir Abbas, Bukhari; Naeem-Ul-Hassan, Muhammad.

In: RSC Advances, Vol. 7, No. 68, 01.01.2017, p. 42900-42908.

Research output: Contribution to journalArticle

Muhammad, G, Hussain, MA, Amin, M, Hussain, SZ, Hussain, I, Syed Nasir Abbas, B & Naeem-Ul-Hassan, M 2017, 'Glucuronoxylan-mediated silver nanoparticles: Green synthesis, antimicrobial and wound healing applications', RSC Advances, vol. 7, no. 68, pp. 42900-42908. https://doi.org/10.1039/c7ra07555c
Muhammad, Gulzar ; Hussain, Muhammad Ajaz ; Amin, Muhammad ; Hussain, Syed Zajif ; Hussain, Irshad ; Syed Nasir Abbas, Bukhari ; Naeem-Ul-Hassan, Muhammad. / Glucuronoxylan-mediated silver nanoparticles : Green synthesis, antimicrobial and wound healing applications. In: RSC Advances. 2017 ; Vol. 7, No. 68. pp. 42900-42908.
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