Gingival and dermal fibroblasts: Their similarities and differences revealed from gene expression

Katsumi Ebisawa, Ryuji Kato, Mai Okada, Tomotaka Sugimura, Mazlyzam Abdul Latif, Yusuke Hori, Yuji Narita, Minoru Ueda, Hiroyuki Honda, Hideaki Kagami

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Gene expression profiles in normal human gingival and dermal fibroblasts were investigated using DNA microarrays. Their fundamental characteristics were almost identical, but 5% of their genes were uniquely expressed. These results help us to choose an optimal cell source for effective fibroblast-based cell therapy that is dependent on differential gene expression profiles.

Original languageEnglish
Pages (from-to)255-258
Number of pages4
JournalJournal of Bioscience and Bioengineering
Volume111
Issue number3
DOIs
Publication statusPublished - Mar 2011

Fingerprint

Fibroblasts
Transcriptome
Gene expression
Gene Expression
Skin
Microarrays
Cell- and Tissue-Based Therapy
Oligonucleotide Array Sequence Analysis
DNA
Genes

Keywords

  • Anti-aging
  • Antioxidant
  • Fibroblast
  • Gingival tissue
  • Microarray

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Bioengineering

Cite this

Gingival and dermal fibroblasts : Their similarities and differences revealed from gene expression. / Ebisawa, Katsumi; Kato, Ryuji; Okada, Mai; Sugimura, Tomotaka; Abdul Latif, Mazlyzam; Hori, Yusuke; Narita, Yuji; Ueda, Minoru; Honda, Hiroyuki; Kagami, Hideaki.

In: Journal of Bioscience and Bioengineering, Vol. 111, No. 3, 03.2011, p. 255-258.

Research output: Contribution to journalArticle

Ebisawa, K, Kato, R, Okada, M, Sugimura, T, Abdul Latif, M, Hori, Y, Narita, Y, Ueda, M, Honda, H & Kagami, H 2011, 'Gingival and dermal fibroblasts: Their similarities and differences revealed from gene expression', Journal of Bioscience and Bioengineering, vol. 111, no. 3, pp. 255-258. https://doi.org/10.1016/j.jbiosc.2010.11.014
Ebisawa, Katsumi ; Kato, Ryuji ; Okada, Mai ; Sugimura, Tomotaka ; Abdul Latif, Mazlyzam ; Hori, Yusuke ; Narita, Yuji ; Ueda, Minoru ; Honda, Hiroyuki ; Kagami, Hideaki. / Gingival and dermal fibroblasts : Their similarities and differences revealed from gene expression. In: Journal of Bioscience and Bioengineering. 2011 ; Vol. 111, No. 3. pp. 255-258.
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