Gingerol and its role in chronic diseases

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Citations (Scopus)

Abstract

Since antiquity, ginger or Zingiber officinale, has been used by humans for medicinal purposes and as spice condiments to enhance flavor in cooking. Ginger contains many phenolic compounds such as gingerol, shogaol and paradol that exhibit antioxidant, anti-tumor and anti-inflammatory properties. The role of ginger and its constituents in ameliorating diseases has been the focus of study in the past two decades by many researchers who provide strong scientific evidence of its health benefit. This review discusses research findings and works devoted to gingerols, the major pungent constituent of ginger, in modulating and targeting signaling pathways with subsequent changes that ameliorate, reverse or prevent chronic diseases in human studies and animal models. The physical, chemical and biological properties of gingerols are also described. The use of ginger and especially gingerols as medicinal food derivative appears to be safe in treating or preventing chronic diseases which will benefit the common population, clinicians, patients, researchers, students and industrialists.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages177-207
Number of pages31
Volume929
DOIs
Publication statusPublished - 2016

Publication series

NameAdvances in Experimental Medicine and Biology
Volume929
ISSN (Print)00652598
ISSN (Electronic)22148019

Fingerprint

Ginger
Chronic Disease
Flavors
Cooking
Condiments
Research Personnel
Tumors
Spices
Animals
Anti-Inflammatory Agents
Antioxidants
Health
Insurance Benefits
Students
Derivatives
gingerol
Animal Models
Food
Research
Population

Keywords

  • Biological properties
  • Chronic diseases
  • Gingerol
  • Physicochemical
  • Signaling pathways

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Mohd Yusof, Y. A. (2016). Gingerol and its role in chronic diseases. In Advances in Experimental Medicine and Biology (Vol. 929, pp. 177-207). (Advances in Experimental Medicine and Biology; Vol. 929). Springer New York LLC. https://doi.org/10.1007/978-3-319-41342-6_8

Gingerol and its role in chronic diseases. / Mohd Yusof, Yasmin Anum.

Advances in Experimental Medicine and Biology. Vol. 929 Springer New York LLC, 2016. p. 177-207 (Advances in Experimental Medicine and Biology; Vol. 929).

Research output: Chapter in Book/Report/Conference proceedingChapter

Mohd Yusof, YA 2016, Gingerol and its role in chronic diseases. in Advances in Experimental Medicine and Biology. vol. 929, Advances in Experimental Medicine and Biology, vol. 929, Springer New York LLC, pp. 177-207. https://doi.org/10.1007/978-3-319-41342-6_8
Mohd Yusof YA. Gingerol and its role in chronic diseases. In Advances in Experimental Medicine and Biology. Vol. 929. Springer New York LLC. 2016. p. 177-207. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-3-319-41342-6_8
Mohd Yusof, Yasmin Anum. / Gingerol and its role in chronic diseases. Advances in Experimental Medicine and Biology. Vol. 929 Springer New York LLC, 2016. pp. 177-207 (Advances in Experimental Medicine and Biology).
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