Gentamicin administration via peritoneal dialysis fluid

The risk of ototoxicity

Balwant Singh Gendeh, H. Said, A. G. Gibb, N. S. Aziz, Z. M. Zahir

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In a prospective study on 47 patients, 16 mg of gentamicin per two litres dialysate was administered intraperitoneally at every cycle of intermittent peritoneal dialysis, carried out over the course of several days. Serum gentamicin sampling, pure tone audiometry and caloric tests were performed before and during the treatment. The gentamicin levels reached at the end of the thirtieth cycle were observed to be low. In view of this, the risk of acute ototoxicity was considered to be minimal. This was confirmed by the absence of clinical audiometric or vestibulometric evidence of toxicity.

Original languageEnglish
Pages (from-to)999-1001
Number of pages3
JournalJournal of Laryngology and Otology
Volume105
Issue number12
Publication statusPublished - 1991

Fingerprint

Ascitic Fluid
Peritoneal Dialysis
Gentamicins
Caloric Tests
Pure-Tone Audiometry
Dialysis Solutions
Prospective Studies
Serum
Therapeutics

Keywords

  • Dialysis
  • Gentamicin
  • Ototoxicity
  • Peritoneal

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Gentamicin administration via peritoneal dialysis fluid : The risk of ototoxicity. / Gendeh, Balwant Singh; Said, H.; Gibb, A. G.; Aziz, N. S.; Zahir, Z. M.

In: Journal of Laryngology and Otology, Vol. 105, No. 12, 1991, p. 999-1001.

Research output: Contribution to journalArticle

Gendeh, BS, Said, H, Gibb, AG, Aziz, NS & Zahir, ZM 1991, 'Gentamicin administration via peritoneal dialysis fluid: The risk of ototoxicity', Journal of Laryngology and Otology, vol. 105, no. 12, pp. 999-1001.
Gendeh, Balwant Singh ; Said, H. ; Gibb, A. G. ; Aziz, N. S. ; Zahir, Z. M. / Gentamicin administration via peritoneal dialysis fluid : The risk of ototoxicity. In: Journal of Laryngology and Otology. 1991 ; Vol. 105, No. 12. pp. 999-1001.
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