Gene expression characteristic in human auricular cartilage tissue engineering.

Farah Wahida Ibrahim, B. S. Aminuddin, S. Munirah, Chua Kien Hui, N. H. Fuzina, M. R. Isa, L. Saim, Ruszymah Idrus

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

This study was to assess collagen type II and collagen type I gene expression in tissue-engineered human auricular: cartilage formed via tissue engineering technique. Large-scale culture expansions were transformed into 3D in vitro construct and were implanted subcutaneously on the dorsal of athymic mice. After 8 weeks, explanted construct was processed in the same manner of native cartilage to facilitate cells for gene expression analysis. Isolated cells from in vivo construct demonstrated expression of type II collagen gene comparable to native cartilage. This study verified that tissue-engineered auricular cartilage expressed cartilage specific gene, collagen type II after in vivo maturation.

Original languageEnglish
Pages (from-to)190-191
Number of pages2
JournalThe Medical journal of Malaysia
Volume59 Suppl B
Publication statusPublished - May 2004

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Ear Cartilage
Collagen Type II
Tissue Engineering
Cartilage
Gene Expression
Collagen Type I
Nude Mice
Genes

ASJC Scopus subject areas

  • Medicine(all)

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Gene expression characteristic in human auricular cartilage tissue engineering. / Ibrahim, Farah Wahida; Aminuddin, B. S.; Munirah, S.; Kien Hui, Chua; Fuzina, N. H.; Isa, M. R.; Saim, L.; Idrus, Ruszymah.

In: The Medical journal of Malaysia, Vol. 59 Suppl B, 05.2004, p. 190-191.

Research output: Contribution to journalArticle

Ibrahim, FW, Aminuddin, BS, Munirah, S, Kien Hui, C, Fuzina, NH, Isa, MR, Saim, L & Idrus, R 2004, 'Gene expression characteristic in human auricular cartilage tissue engineering.', The Medical journal of Malaysia, vol. 59 Suppl B, pp. 190-191.
Ibrahim, Farah Wahida ; Aminuddin, B. S. ; Munirah, S. ; Kien Hui, Chua ; Fuzina, N. H. ; Isa, M. R. ; Saim, L. ; Idrus, Ruszymah. / Gene expression characteristic in human auricular cartilage tissue engineering. In: The Medical journal of Malaysia. 2004 ; Vol. 59 Suppl B. pp. 190-191.
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