Gender differences in the clinical and serological features of systemic lupus erythematosus in Malaysian patients.

M. R. Azizah, S. S. Ainol, N. C. Kong, Y. Normaznah, M. N. Rahim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

An analysis of the clinical and serological features of 12 male and 122 female patients with SLE was done to determine whether sex related differences exist. We found a lower incidence of mucocutaneous symptoms and arthritis but an increased incidence of discoid lesions, pleuritis and pericarditis in males at disease onset. During the disease course, there was a lower incidence of arthritis, a similar prevalence of mucocutaneous symptoms but an increased incidence of pleuritis in males with a trend towards renal involvement. These findings were however not statistically significant except for the higher incidence of thrombosis among males. Serologically, both groups showed similar frequencies of autoantibodies and hypocomplementaemia. Although the study was small, it was shown that several sex-related differences in the clinical and serological features exist in Malaysian SLE patients.

Original languageEnglish
Pages (from-to)302-307
Number of pages6
JournalMedical Journal of Malaysia
Volume56
Issue number3
Publication statusPublished - Sep 2001
Externally publishedYes

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Systemic Lupus Erythematosus
Incidence
Pleurisy
Sex Characteristics
Arthritis
Pericarditis
Autoantibodies
Thrombosis
Kidney

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Azizah, M. R., Ainol, S. S., Kong, N. C., Normaznah, Y., & Rahim, M. N. (2001). Gender differences in the clinical and serological features of systemic lupus erythematosus in Malaysian patients. Medical Journal of Malaysia, 56(3), 302-307.

Gender differences in the clinical and serological features of systemic lupus erythematosus in Malaysian patients. / Azizah, M. R.; Ainol, S. S.; Kong, N. C.; Normaznah, Y.; Rahim, M. N.

In: Medical Journal of Malaysia, Vol. 56, No. 3, 09.2001, p. 302-307.

Research output: Contribution to journalArticle

Azizah, MR, Ainol, SS, Kong, NC, Normaznah, Y & Rahim, MN 2001, 'Gender differences in the clinical and serological features of systemic lupus erythematosus in Malaysian patients.', Medical Journal of Malaysia, vol. 56, no. 3, pp. 302-307.
Azizah, M. R. ; Ainol, S. S. ; Kong, N. C. ; Normaznah, Y. ; Rahim, M. N. / Gender differences in the clinical and serological features of systemic lupus erythematosus in Malaysian patients. In: Medical Journal of Malaysia. 2001 ; Vol. 56, No. 3. pp. 302-307.
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