Functioning adrenal adenoma in association with congenital adrenal hyperplasia

Abdul Ghani Rohana, Wong Ming, Norlela Sukor, M. K. Norazmi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We report a case of a young hypertensive male who was first seen in 1998 with a right thalamic haemorrhage and uncontrolled hypertension. CT abdomen showed a right adrenal tumour and a hyperplastic left adrenal gland. Laparoscopic adrenalectomy performed followed by histopathological examination confirmed the diagnosis of adrenal adenoma. He subsequently presented to us again a year later with persistent hyperkalaemia and asymptomatic hyponatraemia. Further investigations strongly suggested the presence of isolated mineralocorticoid deficiency with normal cortisol levels. This was confirmed to be due to partial or late-onset congenital adrenal hyperplasia (CAH). We discuss the association of partial CAH and adrenal tumours and the unmasking of the mineralocorticoid deficiency following adrenalectomy.

Original languageEnglish
Pages (from-to)158-159
Number of pages2
JournalMedical Journal of Malaysia
Volume62
Issue number2
Publication statusPublished - Jun 2007

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Congenital Adrenal Hyperplasia
Glandular and Epithelial Neoplasms
Adrenalectomy
Adenoma
Mineralocorticoids
Hyperkalemia
Hyponatremia
Adrenal Glands
Abdomen
Hydrocortisone
Hemorrhage
Hypertension
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency
Isolated Mineralocorticoid Deficiency

Keywords

  • Adrenalectomy
  • Conn's adenoma
  • Fludrocortisone
  • Late-onset congenital adrenal hyperplasia (CAH)
  • Mineralocorticoid deficiency

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Functioning adrenal adenoma in association with congenital adrenal hyperplasia. / Rohana, Abdul Ghani; Ming, Wong; Sukor, Norlela; Norazmi, M. K.

In: Medical Journal of Malaysia, Vol. 62, No. 2, 06.2007, p. 158-159.

Research output: Contribution to journalArticle

Rohana, Abdul Ghani ; Ming, Wong ; Sukor, Norlela ; Norazmi, M. K. / Functioning adrenal adenoma in association with congenital adrenal hyperplasia. In: Medical Journal of Malaysia. 2007 ; Vol. 62, No. 2. pp. 158-159.
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