Fine needle aspiration cytology characteristics of renal tumors in children

N. A. Sharifah

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The cytologic findings observed in fine needle aspiration (FNA) biopsy smears from 27 cases of renal tumors in children are reported. The aspirates were from 16 cases of classical Wilms' tumor (WT), one anaplastic WT, 2 clear cell sarcomas of the kidney (CCSK), 2 malignant rhabdoid tumors of the kidney (MRTK) and 6 congenital mesoblastic nephromas (CMNs). The stromal component was present in 16 of the 17 cases (94%) of WT, and the epithelial component in 13 of the cases (76%). Blastema was noted in all 17 cases of WTs. Necrosis was present in 11 (65%) of the smears from WTs. Other features identified include tubular and glomerular differentiation (6 cases), rosette formation (2 cases), striated muscle differentiation (one case) and anaplasia (one case). Smears from malignant rhabdoid tumors of the kidney (MRTK) tended to be very cellular, comprizing cells with prominent esinophilic nucleoli. Cells from clear cell sarcoma of the kidney (CCSK) were usually arranged in smaller discrete groups with fragile cytoplasm. In congenital mesoblastic nephroma (CMN), the cells tend to be spindly and very cohesive. A definite tumor type was able to be made on 25 of the 27 cases (93%) of renal tumors.

Original languageEnglish
Pages (from-to)359-364
Number of pages6
JournalPathology
Volume26
Issue number4
DOIs
Publication statusPublished - 1994
Externally publishedYes

Fingerprint

Fine Needle Biopsy
Cell Biology
Kidney
Wilms Tumor
Mesoblastic Nephroma
Clear Cell Sarcoma
Rhabdoid Tumor
Neoplasms
Anaplasia
Rosette Formation
Striated Muscle
Cytoplasm
Necrosis

Keywords

  • Childhood renal tumors
  • Clear cell sarcoma of the kidney (CCSK)
  • Congenital mesoblastic nephroma (CMN)
  • Fine needle aspiration (FNA)
  • Malignant rhabdoid tumor of the kidney (MRTK)
  • Wilms' tumor (WT)

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Fine needle aspiration cytology characteristics of renal tumors in children. / Sharifah, N. A.

In: Pathology, Vol. 26, No. 4, 1994, p. 359-364.

Research output: Contribution to journalArticle

Sharifah, N. A. / Fine needle aspiration cytology characteristics of renal tumors in children. In: Pathology. 1994 ; Vol. 26, No. 4. pp. 359-364.
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