Ficus carica and bone health: A systematic review

Ruszymah Idrus, Nur Qisya Afifah Veronica Sainik, Ayu Suraya Ansari, Mohamed S. Zulfarina, Rabiatul Adawiyah Razali, Abid Nordin, Aminuddin Bin Saim, Isa Naina Mohamed

Research output: Contribution to journalArticle

Abstract

Ficus carica, a native plant to the Middle East and Western Asia, is of high value in folk medicine. The therapeutic potential of Ficus carica has led to the extensive studies in recent years, focusing on evaluating and validating its pharmacological effect. The present systematic review summarizes the effectiveness of Ficus carica on promoting bone health focusing on osteoporosis and rheumatoid arthritis via mineral contents and RANKL pathway. The search was done with Medline via Ebscohost, Scopus and Google Scholar databases to obtain relevant articles published between 1946 and December 2016. The main inclusion criteria were research articles published in English that reported effect of Ficus carica on bone health. The literature search returned 716 potentially relevant articles, whereby 5 met the inclusion criteria. This systematic review concludes Ficus carica plays an important role in the promotion of bone health and can be a potential pharmaceutical product in the future.

Original languageEnglish
Pages (from-to)2741-2755
Number of pages15
JournalSains Malaysiana
Volume47
Issue number11
DOIs
Publication statusPublished - 1 Nov 2018

Fingerprint

Carica
Ficus
Bone and Bones
Health
Western Asia
Middle East
Far East
Traditional Medicine
Health Promotion
Osteoporosis
Minerals
Rheumatoid Arthritis
Databases
Pharmacology
Research
Pharmaceutical Preparations

Keywords

  • Bone
  • Ficus carica
  • Osteoporosis
  • RANKL pathway
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • General

Cite this

Idrus, R., Sainik, N. Q. A. V., Ansari, A. S., Zulfarina, M. S., Razali, R. A., Nordin, A., ... Naina Mohamed, I. (2018). Ficus carica and bone health: A systematic review. Sains Malaysiana, 47(11), 2741-2755. https://doi.org/10.17576/jsm-2018-4711-17

Ficus carica and bone health : A systematic review. / Idrus, Ruszymah; Sainik, Nur Qisya Afifah Veronica; Ansari, Ayu Suraya; Zulfarina, Mohamed S.; Razali, Rabiatul Adawiyah; Nordin, Abid; Saim, Aminuddin Bin; Naina Mohamed, Isa.

In: Sains Malaysiana, Vol. 47, No. 11, 01.11.2018, p. 2741-2755.

Research output: Contribution to journalArticle

Idrus, R, Sainik, NQAV, Ansari, AS, Zulfarina, MS, Razali, RA, Nordin, A, Saim, AB & Naina Mohamed, I 2018, 'Ficus carica and bone health: A systematic review', Sains Malaysiana, vol. 47, no. 11, pp. 2741-2755. https://doi.org/10.17576/jsm-2018-4711-17
Idrus R, Sainik NQAV, Ansari AS, Zulfarina MS, Razali RA, Nordin A et al. Ficus carica and bone health: A systematic review. Sains Malaysiana. 2018 Nov 1;47(11):2741-2755. https://doi.org/10.17576/jsm-2018-4711-17
Idrus, Ruszymah ; Sainik, Nur Qisya Afifah Veronica ; Ansari, Ayu Suraya ; Zulfarina, Mohamed S. ; Razali, Rabiatul Adawiyah ; Nordin, Abid ; Saim, Aminuddin Bin ; Naina Mohamed, Isa. / Ficus carica and bone health : A systematic review. In: Sains Malaysiana. 2018 ; Vol. 47, No. 11. pp. 2741-2755.
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