Fermentation of gum arabic by gut microbiota using in vitro colon model

Hammad Ahallil, Aminah Abdullah, Mohamad Yusof Maskat, Shahrul R. Sarbini

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

At birth, the human colon is rapidly colonized by gut microbes. Owing to their vast number and their capacity to ferment prebiotics, these gastrointestinal microbes act as an environmental factor that affects the host's physiology and metabolism, particularly in the context of obesity and its related metabolic disorders. In this study, we investigate the effect of gum Arabic (Acacia senegal) as potential prebiotic on human microbiota from obese donors. The effect of Acacia senegal tested using anaerobic, pH-controlled faecal batch cultures system inoculated with human faeces to mimic the distal colon of obese subject. The microbial composition and production of microbial metabolites were monitored at 0, 6, 12, 24 and 36h using fluorescent in situ hybridization (FISH). Acacia senegal was found to modulate the microbiota population, since it significantly increase the growth of Bifidobacterium and decrease the growth of Clostridium. These results identify Acacia senegal as an additional contributing factor to the gut microbiota of obese subjects.

Original languageEnglish
Title of host publication2018 UKM FST Postgraduate Colloquium
Subtitle of host publicationProceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium
EditorsNoor Hayati Ahmad Rasol, Kamarulzaman Ibrahim, Siti Aishah Hasbullah, Mohammad Hafizuddin Hj. Jumali, Nazlina Ibrahim, Marlia Mohd Hanafiah, Mohd Talib Latif
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735418431
DOIs
Publication statusPublished - 27 Jun 2019
Event2018 UKM FST Postgraduate Colloquium - Selangor, Malaysia
Duration: 4 Apr 20186 Apr 2018

Publication series

NameAIP Conference Proceedings
Volume2111
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference2018 UKM FST Postgraduate Colloquium
CountryMalaysia
CitySelangor
Period4/4/186/4/18

Fingerprint

Senegal
Senegalia senegal
fermentation
gum arabic
intestinal microorganisms
colon
obesity
microorganisms
prebiotics
feces
physiology
metabolite
environmental factor
metabolism
Clostridium
metabolites
metabolic diseases
Bifidobacterium
fluorescence in situ hybridization
digestive system

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Ecology
  • Plant Science
  • Physics and Astronomy(all)
  • Nature and Landscape Conservation

Cite this

Ahallil, H., Abdullah, A., Maskat, M. Y., & Sarbini, S. R. (2019). Fermentation of gum arabic by gut microbiota using in vitro colon model. In N. H. A. Rasol, K. Ibrahim, S. A. Hasbullah, M. H. H. Jumali, N. Ibrahim, M. M. Hanafiah, & M. T. Latif (Eds.), 2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium [050004] (AIP Conference Proceedings; Vol. 2111). American Institute of Physics Inc.. https://doi.org/10.1063/1.5111252

Fermentation of gum arabic by gut microbiota using in vitro colon model. / Ahallil, Hammad; Abdullah, Aminah; Maskat, Mohamad Yusof; Sarbini, Shahrul R.

2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium. ed. / Noor Hayati Ahmad Rasol; Kamarulzaman Ibrahim; Siti Aishah Hasbullah; Mohammad Hafizuddin Hj. Jumali; Nazlina Ibrahim; Marlia Mohd Hanafiah; Mohd Talib Latif. American Institute of Physics Inc., 2019. 050004 (AIP Conference Proceedings; Vol. 2111).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ahallil, H, Abdullah, A, Maskat, MY & Sarbini, SR 2019, Fermentation of gum arabic by gut microbiota using in vitro colon model. in NHA Rasol, K Ibrahim, SA Hasbullah, MHH Jumali, N Ibrahim, MM Hanafiah & MT Latif (eds), 2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium., 050004, AIP Conference Proceedings, vol. 2111, American Institute of Physics Inc., 2018 UKM FST Postgraduate Colloquium, Selangor, Malaysia, 4/4/18. https://doi.org/10.1063/1.5111252
Ahallil H, Abdullah A, Maskat MY, Sarbini SR. Fermentation of gum arabic by gut microbiota using in vitro colon model. In Rasol NHA, Ibrahim K, Hasbullah SA, Jumali MHH, Ibrahim N, Hanafiah MM, Latif MT, editors, 2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium. American Institute of Physics Inc. 2019. 050004. (AIP Conference Proceedings). https://doi.org/10.1063/1.5111252
Ahallil, Hammad ; Abdullah, Aminah ; Maskat, Mohamad Yusof ; Sarbini, Shahrul R. / Fermentation of gum arabic by gut microbiota using in vitro colon model. 2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium. editor / Noor Hayati Ahmad Rasol ; Kamarulzaman Ibrahim ; Siti Aishah Hasbullah ; Mohammad Hafizuddin Hj. Jumali ; Nazlina Ibrahim ; Marlia Mohd Hanafiah ; Mohd Talib Latif. American Institute of Physics Inc., 2019. (AIP Conference Proceedings).
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