Fatal acute heart failure secondary to pheochromocytoma: A sudden death case report

Shahrom Abd Wahid, M. A. Razana, M. A. Siti Aishah, H. Zarida

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 36 years old female, was investigated for 'pregnancy induced hypertension' during her pregnancy. The hypertension 'resolved' during the second and third trimester of the pregnancy. She delivered a healthy baby girl and the delivery was uneventful. Her recent admission was due to palpitations, frontal headaches, feeling of nausea with vomiting and epigastric tenderness. She had tachycardia (110/min) and high blood pressure (158/110 mmHg) with cold and clammy hands. ECG showed sinus tachycardia and ST depression (Junctional). Other examination was unremarkable. She was treated with beta blocker. She deteriorated with hypotensive episodes and ECG changes of 2: 1 AV block. She succumbed to her illness and was pronounced dead on the second day of the admission. Postmortem examination revealed the presence of pheochromocytoma, in the right adrenal gland and scattered small foci of myocardial necrosis despite patent coronary vessels. The cause of death was given as acute heart failure secondary to pheochromocytoma. The clinico-pathological aspect of pheochromocytoma in this case is discussed.

Original languageEnglish
Pages (from-to)42-46
Number of pages5
JournalInternational Journal of Medical Toxicology and Legal Medicine
Volume8
Issue number2
Publication statusPublished - Jan 2006

Fingerprint

Pheochromocytoma
Sudden Death
Electrocardiography
Heart Failure
Blood pressure
Sinus Tachycardia
Hypertension
Pregnancy
Pregnancy Induced Hypertension
Atrioventricular Block
Third Pregnancy Trimester
Second Pregnancy Trimester
Adrenal Glands
Tachycardia
Nausea
Vomiting
Headache
Cause of Death
Autopsy
Coronary Vessels

Keywords

  • Adrenal tumour
  • Cathecholamines
  • Chromogranin
  • Heart failure
  • Hypertension
  • Myocardial necrosis
  • Pheochromocytoma

ASJC Scopus subject areas

  • Toxicology
  • Pathology and Forensic Medicine

Cite this

Fatal acute heart failure secondary to pheochromocytoma : A sudden death case report. / Abd Wahid, Shahrom; Razana, M. A.; Siti Aishah, M. A.; Zarida, H.

In: International Journal of Medical Toxicology and Legal Medicine, Vol. 8, No. 2, 01.2006, p. 42-46.

Research output: Contribution to journalArticle

Abd Wahid, Shahrom ; Razana, M. A. ; Siti Aishah, M. A. ; Zarida, H. / Fatal acute heart failure secondary to pheochromocytoma : A sudden death case report. In: International Journal of Medical Toxicology and Legal Medicine. 2006 ; Vol. 8, No. 2. pp. 42-46.
@article{45b87c511e104d29b72ce436eb991dc7,
title = "Fatal acute heart failure secondary to pheochromocytoma: A sudden death case report",
abstract = "A 36 years old female, was investigated for 'pregnancy induced hypertension' during her pregnancy. The hypertension 'resolved' during the second and third trimester of the pregnancy. She delivered a healthy baby girl and the delivery was uneventful. Her recent admission was due to palpitations, frontal headaches, feeling of nausea with vomiting and epigastric tenderness. She had tachycardia (110/min) and high blood pressure (158/110 mmHg) with cold and clammy hands. ECG showed sinus tachycardia and ST depression (Junctional). Other examination was unremarkable. She was treated with beta blocker. She deteriorated with hypotensive episodes and ECG changes of 2: 1 AV block. She succumbed to her illness and was pronounced dead on the second day of the admission. Postmortem examination revealed the presence of pheochromocytoma, in the right adrenal gland and scattered small foci of myocardial necrosis despite patent coronary vessels. The cause of death was given as acute heart failure secondary to pheochromocytoma. The clinico-pathological aspect of pheochromocytoma in this case is discussed.",
keywords = "Adrenal tumour, Cathecholamines, Chromogranin, Heart failure, Hypertension, Myocardial necrosis, Pheochromocytoma",
author = "{Abd Wahid}, Shahrom and Razana, {M. A.} and {Siti Aishah}, {M. A.} and H. Zarida",
year = "2006",
month = "1",
language = "English",
volume = "8",
pages = "42--46",
journal = "International Journal of Medical Toxicology and Legal Medicine",
issn = "0972-0448",
publisher = "All India Institute of Medical Sciences",
number = "2",

}

TY - JOUR

T1 - Fatal acute heart failure secondary to pheochromocytoma

T2 - A sudden death case report

AU - Abd Wahid, Shahrom

AU - Razana, M. A.

AU - Siti Aishah, M. A.

AU - Zarida, H.

PY - 2006/1

Y1 - 2006/1

N2 - A 36 years old female, was investigated for 'pregnancy induced hypertension' during her pregnancy. The hypertension 'resolved' during the second and third trimester of the pregnancy. She delivered a healthy baby girl and the delivery was uneventful. Her recent admission was due to palpitations, frontal headaches, feeling of nausea with vomiting and epigastric tenderness. She had tachycardia (110/min) and high blood pressure (158/110 mmHg) with cold and clammy hands. ECG showed sinus tachycardia and ST depression (Junctional). Other examination was unremarkable. She was treated with beta blocker. She deteriorated with hypotensive episodes and ECG changes of 2: 1 AV block. She succumbed to her illness and was pronounced dead on the second day of the admission. Postmortem examination revealed the presence of pheochromocytoma, in the right adrenal gland and scattered small foci of myocardial necrosis despite patent coronary vessels. The cause of death was given as acute heart failure secondary to pheochromocytoma. The clinico-pathological aspect of pheochromocytoma in this case is discussed.

AB - A 36 years old female, was investigated for 'pregnancy induced hypertension' during her pregnancy. The hypertension 'resolved' during the second and third trimester of the pregnancy. She delivered a healthy baby girl and the delivery was uneventful. Her recent admission was due to palpitations, frontal headaches, feeling of nausea with vomiting and epigastric tenderness. She had tachycardia (110/min) and high blood pressure (158/110 mmHg) with cold and clammy hands. ECG showed sinus tachycardia and ST depression (Junctional). Other examination was unremarkable. She was treated with beta blocker. She deteriorated with hypotensive episodes and ECG changes of 2: 1 AV block. She succumbed to her illness and was pronounced dead on the second day of the admission. Postmortem examination revealed the presence of pheochromocytoma, in the right adrenal gland and scattered small foci of myocardial necrosis despite patent coronary vessels. The cause of death was given as acute heart failure secondary to pheochromocytoma. The clinico-pathological aspect of pheochromocytoma in this case is discussed.

KW - Adrenal tumour

KW - Cathecholamines

KW - Chromogranin

KW - Heart failure

KW - Hypertension

KW - Myocardial necrosis

KW - Pheochromocytoma

UR - http://www.scopus.com/inward/record.url?scp=34247859099&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34247859099&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:34247859099

VL - 8

SP - 42

EP - 46

JO - International Journal of Medical Toxicology and Legal Medicine

JF - International Journal of Medical Toxicology and Legal Medicine

SN - 0972-0448

IS - 2

ER -