Familial pattern of large vestibular aqueduct syndrome in a Chinese family

M. Hazmi, A. Ab Aziz, Asma Abdullah

Research output: Contribution to journalArticle

Abstract

Large Vestibular Aqueduct Syndrome (LVAS) is the most common radiographic malformation in children with early onset of hearing loss. Usually its occurrence is non-familial, however intriguingly a portion of patients with LVAS is found to have evidence of genetic predisposition. We described cases of LVAS in two siblings of a Chinese family. The elder sister first presented with reduced hearing since childhood and her brother has a similar complaint upon further questioning. Their hearing test showed bilateral sensorineural hearing loss (SNHL) and computed tomography (CT) of temporal bone showed enlarged vestibular aqueduct in both patients. We described an approach to diagnosis of LVAS and highlight the importance of hearing assessment in genetic link hearing loss.

Original languageEnglish
Pages (from-to)118-121
Number of pages4
JournalEXCLI Journal
Volume12
Publication statusPublished - 15 Feb 2013

Fingerprint

Vestibular Aqueduct
hearing
Siblings
Hearing Loss
Hearing
Hearing Tests
Bilateral Hearing Loss
Sensorineural Hearing Loss
Temporal Bone
Genetic Predisposition to Disease
Tomography
computed tomography
childhood
bones

Keywords

  • Computed tomography
  • Large Vestibular Aqueduct Syndrome
  • Sensorineural hearing loss

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • Animal Science and Zoology

Cite this

Familial pattern of large vestibular aqueduct syndrome in a Chinese family. / Hazmi, M.; Ab Aziz, A.; Abdullah, Asma.

In: EXCLI Journal, Vol. 12, 15.02.2013, p. 118-121.

Research output: Contribution to journalArticle

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