Factors affecting nutritional status among pediatric patients with transfusion-dependent beta thalassemia

Naghmeh Zahra Mirhosseini, Suzana Shahar, Majid Ghayour-Mobarhan, Nor Azmi Kamaruddin, Abdullah Banihashem, Noor Aini Mohd Yusoff, Habib Alah Esmaili, Shima Tavallaei

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Malnutrition affects the growth, efficacy of treatments and quality of life in children suffering from thalassemia. This study was conducted to assess the nutritional status of thalassemic patients and to determine the factors involved. Data were obtained from 140 thalassemic patients aged 8-18 years in Mashhad, Iran, on anthropometry, food record and biochemical profile. The prevalence of malnutrition was 44.3 % for boys and 19.6 % for girls, as determined by low body mass index. Furthermore, 44.3 % of boys and 37.7 % of girls were found to be of short stature. Sum of triceps and subscapular skinfold thickness and arm muscle area (AMA) calculation showed the incidence of 7.4 % leanness and 60.7 % wasting among thalassemic children and adolescents. The average of energy intake met 74 % of recommended dietary allowance, although more than 71 % under-reporting was calculated for food records. The intake of energy, macronutrients, zinc, iron and vitamin E was positively correlated (P < 0.05) with anthropometric measures. Age, age at first transfusion, age of starting chelation and serum alkaline phosphatase were considered as positive predictors for nutritional status, whereas puberty, gender and fasting blood sugar as negative predictors. Nutritional status of thalassemic children and adolescents should be monitored, focusing on their nutrition education and supplementation, treatment protocol and control on blood sugar. These may play important roles in enhancing the quality of life in thalassemic children and adolescents.

Original languageEnglish
Pages (from-to)45-51
Number of pages7
JournalMediterranean Journal of Nutrition and Metabolism
Volume6
Issue number1
DOIs
Publication statusPublished - Apr 2013

Fingerprint

thalassemia
beta-Thalassemia
Nutritional Status
nutritional status
Pediatrics
food records
Energy Intake
quality of life
Malnutrition
malnutrition
blood glucose
Blood Glucose
energy intake
Quality of Life
Recommended Dietary Allowances
Food
Skinfold Thickness
Anthropometry
Thalassemia
skinfold thickness

Keywords

  • Children
  • Diet
  • Malnutrition
  • Short stature
  • Thalassemia

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Food Science
  • Nutrition and Dietetics

Cite this

Factors affecting nutritional status among pediatric patients with transfusion-dependent beta thalassemia. / Mirhosseini, Naghmeh Zahra; Shahar, Suzana; Ghayour-Mobarhan, Majid; Kamaruddin, Nor Azmi; Banihashem, Abdullah; Yusoff, Noor Aini Mohd; Esmaili, Habib Alah; Tavallaei, Shima.

In: Mediterranean Journal of Nutrition and Metabolism, Vol. 6, No. 1, 04.2013, p. 45-51.

Research output: Contribution to journalArticle

Mirhosseini, Naghmeh Zahra ; Shahar, Suzana ; Ghayour-Mobarhan, Majid ; Kamaruddin, Nor Azmi ; Banihashem, Abdullah ; Yusoff, Noor Aini Mohd ; Esmaili, Habib Alah ; Tavallaei, Shima. / Factors affecting nutritional status among pediatric patients with transfusion-dependent beta thalassemia. In: Mediterranean Journal of Nutrition and Metabolism. 2013 ; Vol. 6, No. 1. pp. 45-51.
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