Factors affecting adherence to antiepileptic drugs therapy in Malaysia

X. C. Tan, Mohd Makmor Bakry, C. L. Lau, F. W. Tajarudin, Raymond Azman Ali

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Poor adherence to antiepileptic drug (AED) therapy can lead to various undesirable complications. Identifying the contributing factors of poor adherence is beneficial in assisting health care professionals to provide optimal interventions to control the seizures. This study aimed to identify the prevalence and factors affecting the adherence level to AED therapy in a multiracial population with epilepsy. This cross-sectional study was conducted at the neurology clinic of a tertiary care setting. Researcherassisted questionnaire was utilised. Adherence level was assessed using validated Modified Morisky Adherence Scale-8. A total of 145 patients with epilepsy were included in this study. The prevalence of poor adherence to AED therapy was 64.1%. Poor adherence level was significantly associated with younger age (χ2 = 7.609, p = 0.022), medication adverse effects (χ2 = 5.075, p = 0.020), shorter duration of epilepsy (r = 0.180, p = 0.030) and uncertainty about the necessity for AEDs (χ2 = 11.803, p = 0.001). Conclusion, prevalence of poor adherence to antiepileptic drugs was high and factors associated with poor adherence to AEDs were identified for a multiracial population with epilepsy.

Original languageEnglish
Pages (from-to)235-241
Number of pages7
JournalNeurology Asia
Volume20
Issue number3
Publication statusPublished - 1 Sep 2015

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Malaysia
Anticonvulsants
Epilepsy
Drug Therapy
Tertiary Healthcare
Neurology
Population
Uncertainty
Seizures
Cross-Sectional Studies
Delivery of Health Care

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Factors affecting adherence to antiepileptic drugs therapy in Malaysia. / Tan, X. C.; Makmor Bakry, Mohd; Lau, C. L.; Tajarudin, F. W.; Ali, Raymond Azman.

In: Neurology Asia, Vol. 20, No. 3, 01.09.2015, p. 235-241.

Research output: Contribution to journalArticle

Tan, X. C. ; Makmor Bakry, Mohd ; Lau, C. L. ; Tajarudin, F. W. ; Ali, Raymond Azman. / Factors affecting adherence to antiepileptic drugs therapy in Malaysia. In: Neurology Asia. 2015 ; Vol. 20, No. 3. pp. 235-241.
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