Evaluation of two types of leukocyte removal filters on transfusion dependent thalassaemics.

A. Rahman A. Jamal, N. R. Mazeni, Noor Hamidah Hussin

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The advent of leukocyte filters has enabled effective removal of leukocytes from certain blood products thus avoiding many adverse effects of blood transfusion. Many different materials have been incorporated into these filters to achieve >95% leukocyte removal. In this study we evaluated the efficacy of leukocyte removal of two different filters, using actual bedside transfusion settings involving patients with transfusion dependent thalassaemia. Fifty-one transfusion events were randomised to use either a polyurethane filter or a non-woven polyester filter. We found that the two filters achieved 98.4% and 96.2% leukocyte removal respectively (p = 0.022). We also found no significant correlation between pre-filtration white blood cell count and the volume transfused with the efficacy of leukodepletion. No untoward events or transfusion reactions were observed during the study.

Original languageEnglish
Pages (from-to)79-83
Number of pages5
JournalThe Malaysian journal of pathology
Volume22
Issue number2
Publication statusPublished - 2000

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Leukocytes
Polyesters
Polyurethanes
Thalassemia
Leukocyte Count
Cell Size
Blood Transfusion

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Evaluation of two types of leukocyte removal filters on transfusion dependent thalassaemics. / A. Jamal, A. Rahman; Mazeni, N. R.; Hussin, Noor Hamidah.

In: The Malaysian journal of pathology, Vol. 22, No. 2, 2000, p. 79-83.

Research output: Contribution to journalArticle

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