Eurycoma Longifolia as a potential adoptogen of male sexual health: a systematic review on clinical studies

Hnin Ei Thu, Isa Naina Mohamed, Zahid Hussain, Putri Ayu Jayusman, Ahmad Nazrun Shuid

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Eurycoma longifolia (EL) has been well recognized as a booster of male sexual health. Over the past few decades, numerous in vivo animal studies and human clinical trials have been conducted across the globe to explore the promising role of EL in managing various male sexual disorders, which include erectile dysfunction, male infertility, low libido, and downregulated testosterone levels. The aim of the present review is to analyze and summarize the literature on human clinical trials which revealed the clinical significance and therapeutic feasibility of EL in improving male sexual health. This systematic review is focused on the following databases: Medline, Wiley Online Library, BioMed Central, Hindawi, Web of Knowledge, PubMed Central and Google Scholar, using search terms such as “Eurycoma longifolia”, “EL”, “Tongkat Ali”, “male sexual health”, “sexual infertility”, “erectile dysfunction”, “male libido”, and “testosterone levels”. Notably, only human clinical studies published between 2000 and 2014 were selected and thoroughly reviewed for relevant citations. Out of 150 articles, 11 met the inclusion criteria. The majority of articles included were randomized placebo-controlled trials, multiple cohort studies, or pilot trials. All these studies demonstrated considerable effects of EL on male sexual health disorders. Among them, 7 studies revealed remarkable association between the use of EL and the efficacy in the treatment of male sexual disorders, and remaining 4 studies failed to demonstrate sufficient effects on male sexual health. In summary, there is convincing evidence for the prominence of EL in improving the male sexual health. The review also substantiates the use of current methodology in the development of novel and more rationale natural herbal medicines for the management of male sexual disorders.

Original languageEnglish
Pages (from-to)71-80
Number of pages10
JournalChinese Journal of Natural Medicines
Volume15
Issue number1
DOIs
Publication statusPublished - 1 Jan 2017

Fingerprint

Eurycoma
Reproductive Health
Libido
Erectile Dysfunction
Testosterone
Clinical Studies
Clinical Trials
Herbal Medicine
Male Infertility
PubMed
Infertility
Libraries

Keywords

  • Erectile dysfunction
  • Eurycoma Longifolia
  • Male infertility
  • Male sexual disorders
  • Sexual libido
  • Testosterone

ASJC Scopus subject areas

  • Drug Discovery
  • Complementary and alternative medicine

Cite this

Eurycoma Longifolia as a potential adoptogen of male sexual health : a systematic review on clinical studies. / Thu, Hnin Ei; Naina Mohamed, Isa; Hussain, Zahid; Jayusman, Putri Ayu; Shuid, Ahmad Nazrun.

In: Chinese Journal of Natural Medicines, Vol. 15, No. 1, 01.01.2017, p. 71-80.

Research output: Contribution to journalArticle

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