Environmental arsenic epidemiology in the Mekong river basin of Cambodia

Kongkea Phan, Kyoung Woong Kim, Jamal Hisham Hashim

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Abstract

    We investigated relationship of arsenicosis symptoms with total blood arsenic (BAs) and serum albumin (SAlb) of residents in the Mekong River basin of Cambodia. We found that arsenicosis patients had significantly higher BAs and lower SAlb than asymptomatic villagers (Mann-Whitney U test, p<0.01). Arsenicosis symptoms were found to be 76.4% (1.764 times) more likely to develop among individuals having an SAlb≤44.3gL-1 than among those who had an SAlb>44.3gL-1 (OR=1.764, 95% CI=0.999-3.114) and 117.6% (2.176 times) as likely to occur among those with BAs>5.73μgL-1 than for those having BAs≤5.73μgL-1 (OR=2.176, 95% CI=1.223-3.872). Furthermore, a significant negative correlation was also found between BAs and SAlb (rs (199)=-0.354, p<0.0001). As such, this study suggests that people with low SAlb and/or high BAs are likely to rapidly develop arsenicosis symptoms.

    Original languageEnglish
    Pages (from-to)37-41
    Number of pages5
    JournalEnvironmental Research
    Volume135
    DOIs
    Publication statusPublished - 1 Nov 2014

    Fingerprint

    Cambodia
    Epidemiology
    Arsenic
    epidemiology
    Rivers
    Catchments
    arsenic
    Blood
    Serum Albumin
    river basin
    blood
    serum
    Nonparametric Statistics
    Serum

    Keywords

    • Arsenicosis
    • Blood arsenic
    • Cambodia
    • Serum albumin
    • Urinary arsenic

    ASJC Scopus subject areas

    • Environmental Science(all)
    • Biochemistry

    Cite this

    Environmental arsenic epidemiology in the Mekong river basin of Cambodia. / Phan, Kongkea; Kim, Kyoung Woong; Hashim, Jamal Hisham.

    In: Environmental Research, Vol. 135, 01.11.2014, p. 37-41.

    Research output: Contribution to journalArticle

    Phan, Kongkea ; Kim, Kyoung Woong ; Hashim, Jamal Hisham. / Environmental arsenic epidemiology in the Mekong river basin of Cambodia. In: Environmental Research. 2014 ; Vol. 135. pp. 37-41.
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