Enteral supplementation of palm vitamin e and alpha-tocopherol

Pre-clinical aspects

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The occurrence of acute gastrointestinal bleeding had been described in 6 % to 100 % in critically ill patients. The morbidity and mortality of patients with critical illnesses are positively correlated with the degree of oxidative stress.Therefore, the administration of antioxidants such as vitamin E seems to be a reasonable therapeutic approach. However, there is conflicting evidence about antioxidant supplementation.This chapter will reveal the scientific evidence of enteral supplementation of vitamin E in the forms of tocotrienol, tocotrienol-rich fraction, and α-tocopherol in animal models of stress. These models mimic the stress endured by criticallyill patients in a clinical setting. The positive outcomes of enteral feeding with vitamin E in reducing the occurrence of stress-induced ulcers are discussed in this chapter. Evidences showing vitamin E’s effects are not just related to its ability to reduce gastric aggressive factors and to maintain gastric protective factors but also on its effects on stress hormones and catecholamines.

Original languageEnglish
Title of host publicationDiet and Nutrition in Critical Care
PublisherSpringer New York
Pages1733-1747
Number of pages15
ISBN (Print)9781461478362, 9781461478379
DOIs
Publication statusPublished - 1 Jan 2015

Fingerprint

alpha-Tocopherol
Vitamin E
Vitamins
Tocotrienols
Small Intestine
Critical Illness
Stomach
Antioxidants
Tocopherols
Enteral Nutrition
Ulcer
Catecholamines
Oxidative stress
Oxidative Stress
Animal Models
Hormones
Hemorrhage
Morbidity
Animals
Mortality

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Enteral supplementation of palm vitamin e and alpha-tocopherol : Pre-clinical aspects. / Mohd Fahami, Nur Azlina; Mohd Saad, Qodriyah; Yusof, Kamisah.

Diet and Nutrition in Critical Care. Springer New York, 2015. p. 1733-1747.

Research output: Chapter in Book/Report/Conference proceedingChapter

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