Enteral glutamine supplementation in surgical patients with head and neck malignancy: A randomized controlled trial

Mawaddah Azman, Mohd. Razif Mohamad Yunus, Suhaina Sulaiman, Syed Nabil Syed Omar

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background Glutamine supplementation is a novel approach to perioperative nutritional management. Methods This study was a prospective randomized clinical trial of effects of enteral glutamine supplementation in surgical patients with head and neck malignancy in a tertiary center. This study measured the effects of supplementation within 4 weeks of the postoncologic surgical period in relation to fat-free mass, serum albumin, and quality of life scores. Results The study population consisted of 44 patients. There was significant difference in serum albumin (p <.001), fat-free mass (p <.001), and quality of life scores (p <.05) between control and interventional groups. Significant correlation exists between fat-free mass and quality of life score difference in our study population (p <.05). Conclusion Enteral glutamine supplementation significantly improves fat-free mass, serum albumin, and quality of life scores postoperatively and maintenance of lean body mass correlated with improved postoperative outcomes in terms of the patient's quality of life.

Original languageEnglish
Pages (from-to)1799-1807
Number of pages9
JournalHead and Neck
Volume37
Issue number12
DOIs
Publication statusPublished - 1 Dec 2015

Fingerprint

Glutamine
Small Intestine
Neck
Randomized Controlled Trials
Head
Quality of Life
Fats
Serum Albumin
Neoplasms
Population
Maintenance
Control Groups

Keywords

  • glutamine
  • head and neck
  • malignancy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Enteral glutamine supplementation in surgical patients with head and neck malignancy : A randomized controlled trial. / Azman, Mawaddah; Mohamad Yunus, Mohd. Razif; Sulaiman, Suhaina; Syed Omar, Syed Nabil.

In: Head and Neck, Vol. 37, No. 12, 01.12.2015, p. 1799-1807.

Research output: Contribution to journalArticle

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