Pengkapsulan nanozarah gadolinium ke dalam vesikel berasaskan asid amino

Translated title of the contribution: Encapsulation of gadolinium nanoparticles in amino acid based vesicles

Muhammad Zul Azri Muhammad Jamil, Faizal K.P. Kunchi Mohamed, Nur Ratasha Alia Md Rosli, Irman Abdul Rahman

Research output: Contribution to journalArticle

Abstract

Production of amino acid based vesicles using sonication method was employed to determine its encapsulation efficacy towards gadolinium(III) nanoparticles as potential drug carrier. The sonication process involved precursor namely sodium N-lauroylsarcosinate hydrate with 1-decanol to produce vesicle in 92 wt.% of water. Gadolinium(III) nanoparticle was then encapsulated into the vesicle system. The structure of Gd2O2CO3 nanoparticles was confirmed by X-ray Diffraction technique (XRD). Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectroscopy indicates the presence of bonding that formed the vesicles. The size distribution of the obtained gadolinium encapsulated vesicle was examined using Transmission Electron Microscopy (TEM). It has been proven to be a potential nano-sized drug carrier.

Original languageMalay
Pages (from-to)1235-1242
Number of pages8
JournalMalaysian Journal of Analytical Sciences
Volume21
Issue number6
DOIs
Publication statusPublished - 1 Dec 2017

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Gadolinium
Encapsulation
Drug Carriers
Sonication
Nanoparticles
Amino Acids
Hydrates
Sodium
Transmission electron microscopy
X ray diffraction
Water

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Pengkapsulan nanozarah gadolinium ke dalam vesikel berasaskan asid amino. / Jamil, Muhammad Zul Azri Muhammad; K.P. Kunchi Mohamed, Faizal; Rosli, Nur Ratasha Alia Md; Abdul Rahman, Irman.

In: Malaysian Journal of Analytical Sciences, Vol. 21, No. 6, 01.12.2017, p. 1235-1242.

Research output: Contribution to journalArticle

Jamil, Muhammad Zul Azri Muhammad ; K.P. Kunchi Mohamed, Faizal ; Rosli, Nur Ratasha Alia Md ; Abdul Rahman, Irman. / Pengkapsulan nanozarah gadolinium ke dalam vesikel berasaskan asid amino. In: Malaysian Journal of Analytical Sciences. 2017 ; Vol. 21, No. 6. pp. 1235-1242.
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