Abstract
Production of amino acid based vesicles using sonication method was employed to determine its encapsulation efficacy towards gadolinium(III) nanoparticles as potential drug carrier. The sonication process involved precursor namely sodium N-lauroylsarcosinate hydrate with 1-decanol to produce vesicle in 92 wt.% of water. Gadolinium(III) nanoparticle was then encapsulated into the vesicle system. The structure of Gd2O2CO3 nanoparticles was confirmed by X-ray Diffraction technique (XRD). Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectroscopy indicates the presence of bonding that formed the vesicles. The size distribution of the obtained gadolinium encapsulated vesicle was examined using Transmission Electron Microscopy (TEM). It has been proven to be a potential nano-sized drug carrier.
| Original language | Malay |
|---|---|
| Pages (from-to) | 1235-1242 |
| Number of pages | 8 |
| Journal | Malaysian Journal of Analytical Sciences |
| Volume | 21 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1 Dec 2017 |
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ASJC Scopus subject areas
- Analytical Chemistry
Cite this
Pengkapsulan nanozarah gadolinium ke dalam vesikel berasaskan asid amino. / Jamil, Muhammad Zul Azri Muhammad; K.P. Kunchi Mohamed, Faizal; Rosli, Nur Ratasha Alia Md; Abdul Rahman, Irman.
In: Malaysian Journal of Analytical Sciences, Vol. 21, No. 6, 01.12.2017, p. 1235-1242.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pengkapsulan nanozarah gadolinium ke dalam vesikel berasaskan asid amino
AU - Jamil, Muhammad Zul Azri Muhammad
AU - K.P. Kunchi Mohamed, Faizal
AU - Rosli, Nur Ratasha Alia Md
AU - Abdul Rahman, Irman
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Production of amino acid based vesicles using sonication method was employed to determine its encapsulation efficacy towards gadolinium(III) nanoparticles as potential drug carrier. The sonication process involved precursor namely sodium N-lauroylsarcosinate hydrate with 1-decanol to produce vesicle in 92 wt.% of water. Gadolinium(III) nanoparticle was then encapsulated into the vesicle system. The structure of Gd2O2CO3 nanoparticles was confirmed by X-ray Diffraction technique (XRD). Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectroscopy indicates the presence of bonding that formed the vesicles. The size distribution of the obtained gadolinium encapsulated vesicle was examined using Transmission Electron Microscopy (TEM). It has been proven to be a potential nano-sized drug carrier.
AB - Production of amino acid based vesicles using sonication method was employed to determine its encapsulation efficacy towards gadolinium(III) nanoparticles as potential drug carrier. The sonication process involved precursor namely sodium N-lauroylsarcosinate hydrate with 1-decanol to produce vesicle in 92 wt.% of water. Gadolinium(III) nanoparticle was then encapsulated into the vesicle system. The structure of Gd2O2CO3 nanoparticles was confirmed by X-ray Diffraction technique (XRD). Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectroscopy indicates the presence of bonding that formed the vesicles. The size distribution of the obtained gadolinium encapsulated vesicle was examined using Transmission Electron Microscopy (TEM). It has been proven to be a potential nano-sized drug carrier.
KW - Drug carrier
KW - Encapsulation
KW - Gadolinium
KW - Sonication
KW - Vesicles
UR - http://www.scopus.com/inward/record.url?scp=85039760156&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85039760156&partnerID=8YFLogxK
U2 - 10.17576/mjas-2017-2106-04
DO - 10.17576/mjas-2017-2106-04
M3 - Article
AN - SCOPUS:85039760156
VL - 21
SP - 1235
EP - 1242
JO - Malaysian Journal of Analytical Sciences
JF - Malaysian Journal of Analytical Sciences
SN - 1394-2506
IS - 6
ER -