EmaxDB

Availability of a first draft genome sequence for the apicomplexan Eimeria maxima

Damer P. Blake, Halimah Alias, Karen J. Billington, Emily L. Clark, Mohd Noor Mat-Isa, Ahmad Fuad Hilmi Mohamad, Mohd Rashdi Mohd-Amin, Yea Ling Tay, Adrian L. Smith, Fiona M. Tomley, Kiew Lian Wan

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Apicomplexan parasites are serious pathogens of animals and man that cause diseases including coccidiosis, malaria and toxoplasmosis. The importance of these parasites has prompted the establishment of genomic resources in support of developing effective control strategies. For the Eimeria species resources have developed most rapidly for the reference Eimeria tenella Houghton strain (http://www.genedb.org/Homepage/Etenella). The value of these resources can be enhanced by comparison with related parasites. The well characterised immunogenicity and genetic diversity associated with Eimeria maxima promote its use in genetics-led studies on coccidiosis and recommended its selection for sequencing. Using a combination of sequencing technologies a first draft assembly and annotation has been produced for an E. maxima Houghton strain-derived clone (EmaxDB; http://www.genomemalaysia.gov.my/emaxdb/). The assembly of a draft genome sequence for E. maxima provides a resource for comparative studies with Eimeria and related parasites as demonstrated here through the identification of genes predicted to encode microneme proteins in E. maxima.

Original languageEnglish
Pages (from-to)48-51
Number of pages4
JournalMolecular and Biochemical Parasitology
Volume184
Issue number1
DOIs
Publication statusPublished - Jul 2012

Fingerprint

Eimeria
Parasites
Genome
Coccidiosis
Eimeria tenella
Toxoplasmosis
Malaria
Clone Cells
Technology
Genes
Proteins

Keywords

  • Database
  • Eimeria maxima
  • Genome sequence
  • Microneme proteins

ASJC Scopus subject areas

  • Molecular Biology
  • Parasitology

Cite this

EmaxDB : Availability of a first draft genome sequence for the apicomplexan Eimeria maxima. / Blake, Damer P.; Alias, Halimah; Billington, Karen J.; Clark, Emily L.; Mat-Isa, Mohd Noor; Mohamad, Ahmad Fuad Hilmi; Mohd-Amin, Mohd Rashdi; Tay, Yea Ling; Smith, Adrian L.; Tomley, Fiona M.; Wan, Kiew Lian.

In: Molecular and Biochemical Parasitology, Vol. 184, No. 1, 07.2012, p. 48-51.

Research output: Contribution to journalArticle

Blake, DP, Alias, H, Billington, KJ, Clark, EL, Mat-Isa, MN, Mohamad, AFH, Mohd-Amin, MR, Tay, YL, Smith, AL, Tomley, FM & Wan, KL 2012, 'EmaxDB: Availability of a first draft genome sequence for the apicomplexan Eimeria maxima', Molecular and Biochemical Parasitology, vol. 184, no. 1, pp. 48-51. https://doi.org/10.1016/j.molbiopara.2012.03.004
Blake, Damer P. ; Alias, Halimah ; Billington, Karen J. ; Clark, Emily L. ; Mat-Isa, Mohd Noor ; Mohamad, Ahmad Fuad Hilmi ; Mohd-Amin, Mohd Rashdi ; Tay, Yea Ling ; Smith, Adrian L. ; Tomley, Fiona M. ; Wan, Kiew Lian. / EmaxDB : Availability of a first draft genome sequence for the apicomplexan Eimeria maxima. In: Molecular and Biochemical Parasitology. 2012 ; Vol. 184, No. 1. pp. 48-51.
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