Effects of testosterone on blood leukocytes in Plasmodium berghei-infected mice

A. B. Kamis, Ibrahim Jantan

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Gonadectomized male mice aged 5 weeks were given 5 mg testosterone propionate daily for 14 days. The treatment significantly decreased the number of blood leukocytes. The number of all individual types of leukocytes except basophils in vehicle-treated gonadectomized mice was increased. Testosterone-treated mice consistently had a lower number of leukocytes after being infected with Plasmodium berghei than did vehicle-treated mice. The results suggest that testosterone suppresses the production of leukocytes and that testosterone-treated mice become more susceptible to parasite infection.

Original languageEnglish
Pages (from-to)611-613
Number of pages3
JournalParasitology Research
Volume75
Issue number8
DOIs
Publication statusPublished - Aug 1989

Fingerprint

Plasmodium berghei
testosterone
Testosterone
leukocytes
Leukocytes
blood
mice
Leukocyte Count
Testosterone Propionate
Parasitic Diseases
basophils
Basophils
propionates
leukocyte count
parasites
infection

ASJC Scopus subject areas

  • Parasitology

Cite this

Effects of testosterone on blood leukocytes in Plasmodium berghei-infected mice. / Kamis, A. B.; Jantan, Ibrahim.

In: Parasitology Research, Vol. 75, No. 8, 08.1989, p. 611-613.

Research output: Contribution to journalArticle

Kamis, A. B. ; Jantan, Ibrahim. / Effects of testosterone on blood leukocytes in Plasmodium berghei-infected mice. In: Parasitology Research. 1989 ; Vol. 75, No. 8. pp. 611-613.
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