Effects of aqueous extract of rafflesia cantleyi bud on aphrodisiac activity in male sprague dawley rats

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Abstract

Rafflesia cantleyi is locally known as Bunga Pakma has been used in Malaysian folk medicine by men as an energy drink or an aphrodisiac. However, there has been no evaluation of the effect of the repeated dosing of R. cantleyi bud. The current work was undertaken to evaluate the acclaimed aphrodisiac activity of R. cantleyi bud on male rats. The 40 adult male rats were divided into 4 groups (n =10 per group/dose). Rats in group A (control) were administered with 1 mL of distilled water while those in groups B, C and D were given same volume containing 250, 500 and 1000 mg kg-1 b.wt., of R. cantleyi bud water extract, respectively for 28 days. The effect of the extract on body weight, reproductive organ weight and serum testosterone concentration were determined. Sexual behavior parameters were monitored in male rats for weekly mounting test and on day 28 by pairing with a receptive female (1:1). The results revealed that the R. cantleyi bud water extract significantly increase body weight and serum testosterone content (p-1 b.wt. significantly increase the frequency of mount and intromission (p

Original languageEnglish
Pages (from-to)938-943
Number of pages6
JournalInternational Journal of Pharmacology
Volume11
Issue number8
DOIs
Publication statusPublished - 2015

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Aphrodisiacs
Sprague Dawley Rats
Testosterone
Water
Energy Drinks
Body Weight
Organ Size
Traditional Medicine
Serum
Sexual Behavior
Control Groups

Keywords

  • Aphrodisiac
  • Rafflesia cantleyi bud
  • Sexual behavior
  • Sprague dawley male rats

ASJC Scopus subject areas

  • Pharmacology

Cite this

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abstract = "Rafflesia cantleyi is locally known as Bunga Pakma has been used in Malaysian folk medicine by men as an energy drink or an aphrodisiac. However, there has been no evaluation of the effect of the repeated dosing of R. cantleyi bud. The current work was undertaken to evaluate the acclaimed aphrodisiac activity of R. cantleyi bud on male rats. The 40 adult male rats were divided into 4 groups (n =10 per group/dose). Rats in group A (control) were administered with 1 mL of distilled water while those in groups B, C and D were given same volume containing 250, 500 and 1000 mg kg-1 b.wt., of R. cantleyi bud water extract, respectively for 28 days. The effect of the extract on body weight, reproductive organ weight and serum testosterone concentration were determined. Sexual behavior parameters were monitored in male rats for weekly mounting test and on day 28 by pairing with a receptive female (1:1). The results revealed that the R. cantleyi bud water extract significantly increase body weight and serum testosterone content (p-1 b.wt. significantly increase the frequency of mount and intromission (p",
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AU - Ibrahim, Nazlina

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