Kesan Penuaan ke atas Kehubungan Berkesan Otak semasa Pemprosesan Persepsi Pertuturan daripada Perspektif Pemodelan Sebab dan Akibat Dinamik

Satu Kajian fMRI

Translated title of the contribution: Effects of aging on effective brain connectivity during speech perception processing from dynamic causal modeling perspective: An fMRI study

Hanani Abdul Manan, Ahmad Nazlim Yusoff, Siti Zamratol Mai Sarah Mukari

Research output: Contribution to journalArticle

Abstract

Aging process is often associated with a deterioration in cognitive system. The decline begins as early as in the twenties and continues linearly. Other than that, the decline also becomes more pronounced in the presence of background noise. However, the effects of aging on the mechanisms of speech perception processing using forward repeat task (FRT) in quiet and in noise have not yet clearly understood. In this study, functional magnetic resonance imaging (fMRI) was used to compare the effects of aging on effective connectivity resulting from FRT tasks on normal subjects with four different age groups which are 20 - 29 years (n = 15), 30 - 39 years (n = 15), 40 - 49 years (n = 10) and 50 - 65 years (n = 14). A series of five words interspersed in noise and in quiet were given using auditory stimulus. Statistical parametric mapping (SPM8) and dynamic causal modeling (DCM10) was used to determine the effective connectivity. Three areas, STG, HG and PCG were selected to built effective connectivity models. The effective connectivity results using FRT task showed there is no significant changes in the intrahemispheric connectivity when a person gets older, however the interhemispheric communication becomes more complex.

Original languageMalay
Pages (from-to)1843-1852
Number of pages10
JournalSains Malaysiana
Volume47
Issue number8
DOIs
Publication statusPublished - 1 Aug 2018

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Speech Perception
Noise
Magnetic Resonance Imaging
Brain
Age Groups
Communication

ASJC Scopus subject areas

  • General

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Kesan Penuaan ke atas Kehubungan Berkesan Otak semasa Pemprosesan Persepsi Pertuturan daripada Perspektif Pemodelan Sebab dan Akibat Dinamik : Satu Kajian fMRI. / Manan, Hanani Abdul; Yusoff, Ahmad Nazlim; Mukari, Siti Zamratol Mai Sarah.

In: Sains Malaysiana, Vol. 47, No. 8, 01.08.2018, p. 1843-1852.

Research output: Contribution to journalArticle

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