Effectiveness of tramadol/paracetamol compared with etoricoxib as postoperative analgesia in daycare surgery

Choy Y. Choy, Adnan Isquandar

    Research output: Contribution to journalArticle

    Abstract

    Objective: The objective was to evaluate the effectiveness of a fixed, tramadol/paracetamol combination when compared with etoricoxib as postoperative analgesia following day care surgery. Design: This was a prospective, randomised, single-blind study. Setting and subjects: Sixty-two patients were randomised to receive either etoricoxib (n = 29) or tramadol/paracetamol (n = 33) by mouth prior to surgery. Patients were given general anaesthesia with fentanyl for intraoperative and rescue analgesia. Outcome measures: The primary efficacy variables that were investigated were total pain relief and sum of pain intensity differences at 1, 2, 3, 4, 6, 24 and 48 hours. Data were collected by an independent observer through an interview or by telephone after discharge. Results: Total pain relief (p-value 0.001) was significantly different between the two groups for the first four hours. The total dose of fentanyl use was comparable between the two groups. There was also a significant difference in the occurrence of nausea with tramadol/paracetamol (p-value 0.001), and dizziness with etoricoxib (p-value 0.024). Conclusion: Tramadol/paracetamol provided significantly better pain relief than etoricoxib in the early postoperative period.

    Original languageEnglish
    Pages (from-to)155-159
    Number of pages5
    JournalSouthern African Journal of Anaesthesia and Analgesia
    Volume20
    Issue number3
    DOIs
    Publication statusPublished - 2014

    Fingerprint

    etoricoxib
    Tramadol
    Acetaminophen
    Analgesia
    Pain
    Fentanyl
    Single-Blind Method
    Dizziness
    Ambulatory Surgical Procedures
    Postoperative Period
    General Anesthesia
    Nausea
    Mouth
    Outcome Assessment (Health Care)
    Interviews

    Keywords

    • Daycare surgery
    • Etoricoxib
    • Paracetamol
    • Postoperative analgesia
    • Tramadol

    ASJC Scopus subject areas

    • Anesthesiology and Pain Medicine

    Cite this

    Effectiveness of tramadol/paracetamol compared with etoricoxib as postoperative analgesia in daycare surgery. / Choy, Choy Y.; Isquandar, Adnan.

    In: Southern African Journal of Anaesthesia and Analgesia, Vol. 20, No. 3, 2014, p. 155-159.

    Research output: Contribution to journalArticle

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