Effect of water extract of Labisia pumila Var Alata on aorta of ovariectomized Sprague Dawley rats

Ayida Al-Wahaibi, W. M. Wan Nazaimoon, W. N. Norsyam, Farihah Suhaimi, A. L. Azian

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Labisia pumila var alata, locally known Kacip Fatimah, is a traditional herb used by Malay women to induce and facilitate childbirth as well as to increase a woman's libido. This study was aimed to investigate the effect of Labisia pumila consumption on maintaining the integrity of the aortic wall in ovariectomized rats. Thirty-five adult female Sprague Dawley rats, 6 months old, were used in the experiment. Rats were divided into Normal (NOR) and ovariectomized (OVKC, KF and ERT) groups. Body weight was checked and recorded monthly. After four months, rats were sacrificed by cervical dislocation and tissue samples from the aorta were collected for histological studies. Results showed that water extract of Labisia pumila-treatment maintained the elastic lamellae architecture of the oyariectomized rat aortae in a manner comparable to that of the normal rats. Results implied a possible role for labisia pumila in modulating postmenopausal cardiovascular risks.

Original languageEnglish
Pages (from-to)208-213
Number of pages6
JournalPakistan Journal of Nutrition
Volume7
Issue number2
Publication statusPublished - 2008

Fingerprint

aorta
Sprague Dawley Rats
Aorta
Water
rats
extracts
water
Libido
cervical dislocation
childbirth
libido
Body Weight
Parturition
herbs
body weight
sampling
Therapeutics

Keywords

  • Aorta
  • Labisia pumila var alata
  • Ovariectomy

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics
  • Public Health, Environmental and Occupational Health

Cite this

Al-Wahaibi, A., Wan Nazaimoon, W. M., Norsyam, W. N., Suhaimi, F., & Azian, A. L. (2008). Effect of water extract of Labisia pumila Var Alata on aorta of ovariectomized Sprague Dawley rats. Pakistan Journal of Nutrition, 7(2), 208-213.

Effect of water extract of Labisia pumila Var Alata on aorta of ovariectomized Sprague Dawley rats. / Al-Wahaibi, Ayida; Wan Nazaimoon, W. M.; Norsyam, W. N.; Suhaimi, Farihah; Azian, A. L.

In: Pakistan Journal of Nutrition, Vol. 7, No. 2, 2008, p. 208-213.

Research output: Contribution to journalArticle

Al-Wahaibi, A, Wan Nazaimoon, WM, Norsyam, WN, Suhaimi, F & Azian, AL 2008, 'Effect of water extract of Labisia pumila Var Alata on aorta of ovariectomized Sprague Dawley rats', Pakistan Journal of Nutrition, vol. 7, no. 2, pp. 208-213.
Al-Wahaibi, Ayida ; Wan Nazaimoon, W. M. ; Norsyam, W. N. ; Suhaimi, Farihah ; Azian, A. L. / Effect of water extract of Labisia pumila Var Alata on aorta of ovariectomized Sprague Dawley rats. In: Pakistan Journal of Nutrition. 2008 ; Vol. 7, No. 2. pp. 208-213.
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