Effect of nicotine and goat milk co-administration on rat testis and sperm parameters

A. M. Anum Fairuz, N. H. Hashida, Mahanem Mat Noor

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The present study was conducted to observe the beneficial effect of goat milk on the sperm parameters of nicotine treated rats. Sprague Dawley juvenile rats (5 to 6 weeks old) were randomly divided into three groups. For nicotine (N) and goat milk (GM) groups, the rats were daily injected with 5.0mg/kg body weight of nicotine and force-fed with 20.0ml/kg body weight of goat milk, respectively. However, for nicotine with goat milk (N-GM) group, the rats were injected with 5.0mg/kg body weight of nicotine and force-fed with 20.0ml/kg body weight of goat milk. After 60 days of treatments, the rats were sacrificed and the reproductive organs were removed. Sperm were collected from epididymis and assessed for sperm count, viability and morphology. Goat milk (GM) group showed higher sperm count (40.30±13.39 × 10 5/ml), more live sperm (385.49±12.97) and more normal sperm (188.31±0.61) than N and N-GM groups (P<0.05). However, co-administration of nicotine with goat milk (N-GM) gave higher sperm parameters values as compared to that observe in N group (P<0.05). This study suggested that goat milk is potentially useful in increasing the fertility of nicotine treated male rats.

Original languageEnglish
Pages (from-to)2738-2741
Number of pages4
JournalAustralian Journal of Basic and Applied Sciences
Volume5
Issue number12
Publication statusPublished - Dec 2011

Fingerprint

nicotine
goat milk
testes
spermatozoa
rats
body weight
epididymis
gonads
viability

Keywords

  • Goat milk
  • Nicotine
  • Sperm quality
  • Sprague Dawley rats

ASJC Scopus subject areas

  • General

Cite this

Effect of nicotine and goat milk co-administration on rat testis and sperm parameters. / Anum Fairuz, A. M.; Hashida, N. H.; Mat Noor, Mahanem.

In: Australian Journal of Basic and Applied Sciences, Vol. 5, No. 12, 12.2011, p. 2738-2741.

Research output: Contribution to journalArticle

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