Effect of microchannel sizes on 3D hydrodynamic focusing of a microflow cytometer

Norasyikin Selamat, Muhammad Syafiq Bin Rahim, Abang Annuar Ehsan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Hydrodynamic focusing is an important method used in microfluidics cell sorting devices. A design of flow cytometer has been developed and simulated using COMSOL Multyphysics software. The device is capable of creating a self-aligned stream by manipulating the flow rate, Q in both sheath channel. The objective of this research is to study the effect of channel size variation on the fluid flow in the micro flow cytometer device. The flow rate ratio Qs/Qi is applied in order find the best flow rate ratio value between sheath channel and sample channel. Simulated results showed that when Qs is smaller than Qi, the stream size is bigger and the length of the stream is longer. However, Qs is equal to Qi, the stream becomes smaller and the length of the stream is shorter. Similary, when Qs is bigger than Qi, the stream becomes smaller and shorter. The results showed that fluid flow is better when the size of the channel is bigger.

Original languageEnglish
Title of host publication2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages109-112
Number of pages4
Volume2016-September
ISBN (Electronic)9781509023837
DOIs
Publication statusPublished - 21 Sep 2016
Event12th IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Bangsar, Kuala Lumpur, Malaysia
Duration: 17 Aug 201619 Aug 2016

Other

Other12th IEEE International Conference on Semiconductor Electronics, ICSE 2016
CountryMalaysia
CityBangsar, Kuala Lumpur
Period17/8/1619/8/16

Fingerprint

Microchannels
Hydrodynamics
Flow rate
Flow of fluids
Sorting
Microfluidics
Cells

Keywords

  • comsol
  • hyfrodynamic focusing
  • microflow cytometer
  • microfluidics

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

Cite this

Selamat, N., Rahim, M. S. B., & Ehsan, A. A. (2016). Effect of microchannel sizes on 3D hydrodynamic focusing of a microflow cytometer. In 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings (Vol. 2016-September, pp. 109-112). [7573603] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SMELEC.2016.7573603

Effect of microchannel sizes on 3D hydrodynamic focusing of a microflow cytometer. / Selamat, Norasyikin; Rahim, Muhammad Syafiq Bin; Ehsan, Abang Annuar.

2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings. Vol. 2016-September Institute of Electrical and Electronics Engineers Inc., 2016. p. 109-112 7573603.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Selamat, N, Rahim, MSB & Ehsan, AA 2016, Effect of microchannel sizes on 3D hydrodynamic focusing of a microflow cytometer. in 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings. vol. 2016-September, 7573603, Institute of Electrical and Electronics Engineers Inc., pp. 109-112, 12th IEEE International Conference on Semiconductor Electronics, ICSE 2016, Bangsar, Kuala Lumpur, Malaysia, 17/8/16. https://doi.org/10.1109/SMELEC.2016.7573603
Selamat N, Rahim MSB, Ehsan AA. Effect of microchannel sizes on 3D hydrodynamic focusing of a microflow cytometer. In 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings. Vol. 2016-September. Institute of Electrical and Electronics Engineers Inc. 2016. p. 109-112. 7573603 https://doi.org/10.1109/SMELEC.2016.7573603
Selamat, Norasyikin ; Rahim, Muhammad Syafiq Bin ; Ehsan, Abang Annuar. / Effect of microchannel sizes on 3D hydrodynamic focusing of a microflow cytometer. 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings. Vol. 2016-September Institute of Electrical and Electronics Engineers Inc., 2016. pp. 109-112
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