Effect of geometrical shapes on 3D hydrodynamic focusing of a microfluidic flow cytometer

Muhammad Syafiq Rahim, Norasyikin Selamat, Jumril Yunas, Abang Annuar Ehsan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

This paper focuses on the effect of geometrical cross section between rectangular and circular shapes on the hydrodynamic focusing of a micro flow cytometer device. The effect of fluid flow ratio between the main and sheath channels on the focusing width is studied. This study has been performed using a COMSOL Multiphysics simulation tool. The results showed that focusing width decreases as the ratio between main channel and sheath channels are increased. The concentration at long-range is studied and indicated that circular shape can sustain a higher concentration at the centre along the channel compared with rectangular shape. The velocity at the cross-section of the channel-junction shows that circular shape produces higher velocity at the centre of the channel compare to that of the rectangular shape. The effect of flow ratio and geometrical shape are significantly vital for microfluidic system which utilizes hydrodynamic focusing for biological and chemical analysis. From the result, micro flow cytometer studied able to use for human body cells such as glucose, virus, red blood cells and white blood cells which have a range size of 2-120 microns.

Original languageEnglish
Title of host publication2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages113-116
Number of pages4
Volume2016-September
ISBN (Electronic)9781509023837
DOIs
Publication statusPublished - 21 Sep 2016
Event12th IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Bangsar, Kuala Lumpur, Malaysia
Duration: 17 Aug 201619 Aug 2016

Other

Other12th IEEE International Conference on Semiconductor Electronics, ICSE 2016
CountryMalaysia
CityBangsar, Kuala Lumpur
Period17/8/1619/8/16

Fingerprint

Microfluidics
Blood
Hydrodynamics
Cells
Viruses
Glucose
Flow of fluids
Chemical analysis

Keywords

  • comsol
  • fluid flow
  • hydrodynamic focusing
  • microchanne
  • microflow cytometer
  • microfluidics
  • microfluidics devices

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

Cite this

Rahim, M. S., Selamat, N., Yunas, J., & Ehsan, A. A. (2016). Effect of geometrical shapes on 3D hydrodynamic focusing of a microfluidic flow cytometer. In 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings (Vol. 2016-September, pp. 113-116). [7573604] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SMELEC.2016.7573604

Effect of geometrical shapes on 3D hydrodynamic focusing of a microfluidic flow cytometer. / Rahim, Muhammad Syafiq; Selamat, Norasyikin; Yunas, Jumril; Ehsan, Abang Annuar.

2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings. Vol. 2016-September Institute of Electrical and Electronics Engineers Inc., 2016. p. 113-116 7573604.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rahim, MS, Selamat, N, Yunas, J & Ehsan, AA 2016, Effect of geometrical shapes on 3D hydrodynamic focusing of a microfluidic flow cytometer. in 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings. vol. 2016-September, 7573604, Institute of Electrical and Electronics Engineers Inc., pp. 113-116, 12th IEEE International Conference on Semiconductor Electronics, ICSE 2016, Bangsar, Kuala Lumpur, Malaysia, 17/8/16. https://doi.org/10.1109/SMELEC.2016.7573604
Rahim MS, Selamat N, Yunas J, Ehsan AA. Effect of geometrical shapes on 3D hydrodynamic focusing of a microfluidic flow cytometer. In 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings. Vol. 2016-September. Institute of Electrical and Electronics Engineers Inc. 2016. p. 113-116. 7573604 https://doi.org/10.1109/SMELEC.2016.7573604
Rahim, Muhammad Syafiq ; Selamat, Norasyikin ; Yunas, Jumril ; Ehsan, Abang Annuar. / Effect of geometrical shapes on 3D hydrodynamic focusing of a microfluidic flow cytometer. 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings. Vol. 2016-September Institute of Electrical and Electronics Engineers Inc., 2016. pp. 113-116
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