Abstract
This paper focuses on the effect of geometrical cross section between rectangular and circular shapes on the hydrodynamic focusing of a micro flow cytometer device. The effect of fluid flow ratio between the main and sheath channels on the focusing width is studied. This study has been performed using a COMSOL Multiphysics simulation tool. The results showed that focusing width decreases as the ratio between main channel and sheath channels are increased. The concentration at long-range is studied and indicated that circular shape can sustain a higher concentration at the centre along the channel compared with rectangular shape. The velocity at the cross-section of the channel-junction shows that circular shape produces higher velocity at the centre of the channel compare to that of the rectangular shape. The effect of flow ratio and geometrical shape are significantly vital for microfluidic system which utilizes hydrodynamic focusing for biological and chemical analysis. From the result, micro flow cytometer studied able to use for human body cells such as glucose, virus, red blood cells and white blood cells which have a range size of 2-120 microns.
| Original language | English |
|---|---|
| Title of host publication | 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 113-116 |
| Number of pages | 4 |
| Volume | 2016-September |
| ISBN (Electronic) | 9781509023837 |
| DOIs | |
| Publication status | Published - 21 Sep 2016 |
| Event | 12th IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Bangsar, Kuala Lumpur, Malaysia Duration: 17 Aug 2016 → 19 Aug 2016 |
Other
| Other | 12th IEEE International Conference on Semiconductor Electronics, ICSE 2016 |
|---|---|
| Country | Malaysia |
| City | Bangsar, Kuala Lumpur |
| Period | 17/8/16 → 19/8/16 |
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Keywords
- comsol
- fluid flow
- hydrodynamic focusing
- microchanne
- microflow cytometer
- microfluidics
- microfluidics devices
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Electronic, Optical and Magnetic Materials
Cite this
Effect of geometrical shapes on 3D hydrodynamic focusing of a microfluidic flow cytometer. / Rahim, Muhammad Syafiq; Selamat, Norasyikin; Yunas, Jumril; Ehsan, Abang Annuar.
2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings. Vol. 2016-September Institute of Electrical and Electronics Engineers Inc., 2016. p. 113-116 7573604.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Effect of geometrical shapes on 3D hydrodynamic focusing of a microfluidic flow cytometer
AU - Rahim, Muhammad Syafiq
AU - Selamat, Norasyikin
AU - Yunas, Jumril
AU - Ehsan, Abang Annuar
PY - 2016/9/21
Y1 - 2016/9/21
N2 - This paper focuses on the effect of geometrical cross section between rectangular and circular shapes on the hydrodynamic focusing of a micro flow cytometer device. The effect of fluid flow ratio between the main and sheath channels on the focusing width is studied. This study has been performed using a COMSOL Multiphysics simulation tool. The results showed that focusing width decreases as the ratio between main channel and sheath channels are increased. The concentration at long-range is studied and indicated that circular shape can sustain a higher concentration at the centre along the channel compared with rectangular shape. The velocity at the cross-section of the channel-junction shows that circular shape produces higher velocity at the centre of the channel compare to that of the rectangular shape. The effect of flow ratio and geometrical shape are significantly vital for microfluidic system which utilizes hydrodynamic focusing for biological and chemical analysis. From the result, micro flow cytometer studied able to use for human body cells such as glucose, virus, red blood cells and white blood cells which have a range size of 2-120 microns.
AB - This paper focuses on the effect of geometrical cross section between rectangular and circular shapes on the hydrodynamic focusing of a micro flow cytometer device. The effect of fluid flow ratio between the main and sheath channels on the focusing width is studied. This study has been performed using a COMSOL Multiphysics simulation tool. The results showed that focusing width decreases as the ratio between main channel and sheath channels are increased. The concentration at long-range is studied and indicated that circular shape can sustain a higher concentration at the centre along the channel compared with rectangular shape. The velocity at the cross-section of the channel-junction shows that circular shape produces higher velocity at the centre of the channel compare to that of the rectangular shape. The effect of flow ratio and geometrical shape are significantly vital for microfluidic system which utilizes hydrodynamic focusing for biological and chemical analysis. From the result, micro flow cytometer studied able to use for human body cells such as glucose, virus, red blood cells and white blood cells which have a range size of 2-120 microns.
KW - comsol
KW - fluid flow
KW - hydrodynamic focusing
KW - microchanne
KW - microflow cytometer
KW - microfluidics
KW - microfluidics devices
UR - http://www.scopus.com/inward/record.url?scp=84990982141&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84990982141&partnerID=8YFLogxK
U2 - 10.1109/SMELEC.2016.7573604
DO - 10.1109/SMELEC.2016.7573604
M3 - Conference contribution
AN - SCOPUS:84990982141
VL - 2016-September
SP - 113
EP - 116
BT - 2016 IEEE International Conference on Semiconductor Electronics, ICSE 2016 - Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
ER -