Effect of gender and age on fasting serum growth hormone levels in normal subjects.

W. M. Nazaimoon, M. L. Ng, A. Osman, T. T. Tan, Loo Ling Wu, B. A. Khalid

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Fasting growth hormone (GH) level is an important reference level in dynamic tests of GH secretion. Other studies have demonstrated sex and age variation in the rate of GH secretion. We analysed fasting serum samples from 377 normal subjects (193 males and 184 females, age range 6 to 81 years old), using our in-house enzyme immunoassay. We found sex differences in fasting GH levels to be only significant in the prepubertal children (Tanner stage I), being higher in girls than in age-matched boys (p < 0.05). Both sexes showed age-dependent changes in fasting GH levels (p < 0.001); highest levels were achieved at puberty and subsequently declined with advancing age. Hence, the physiological sex difference and age-dependency in GH secretion can also be demonstrated in single fasting samples.

Original languageEnglish
Pages (from-to)297-302
Number of pages6
JournalMedical Journal of Malaysia
Volume48
Issue number3
Publication statusPublished - Sep 1993

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Growth Hormone
Fasting
Serum
Sex Characteristics
Puberty
Immunoenzyme Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nazaimoon, W. M., Ng, M. L., Osman, A., Tan, T. T., Wu, L. L., & Khalid, B. A. (1993). Effect of gender and age on fasting serum growth hormone levels in normal subjects. Medical Journal of Malaysia, 48(3), 297-302.

Effect of gender and age on fasting serum growth hormone levels in normal subjects. / Nazaimoon, W. M.; Ng, M. L.; Osman, A.; Tan, T. T.; Wu, Loo Ling; Khalid, B. A.

In: Medical Journal of Malaysia, Vol. 48, No. 3, 09.1993, p. 297-302.

Research output: Contribution to journalArticle

Nazaimoon, WM, Ng, ML, Osman, A, Tan, TT, Wu, LL & Khalid, BA 1993, 'Effect of gender and age on fasting serum growth hormone levels in normal subjects.', Medical Journal of Malaysia, vol. 48, no. 3, pp. 297-302.
Nazaimoon, W. M. ; Ng, M. L. ; Osman, A. ; Tan, T. T. ; Wu, Loo Ling ; Khalid, B. A. / Effect of gender and age on fasting serum growth hormone levels in normal subjects. In: Medical Journal of Malaysia. 1993 ; Vol. 48, No. 3. pp. 297-302.
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