Effect of different concentrations of red palm olein onantioxidant enzymes activity of rat liver

Eqbal Dauqan, Halimah Abdullah Sani, Aminah Abdullah, Zalifah Mohd Kasim

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Abstract

The objective of this study was to evaluate the effect of different concentrations of red palm olein (RPO)on antioxidant enzymes activity of rat liver. Seventy eight (78) rats were randomly divided into thirteen(13) groups of 6 rats per group and treated with different concentrations of RPO (5, 10 and 15%) for 2, 4and 8 weeks. Rats in the control group were given normal rat pellet only, while those in treated groups,5, 10 and 15% of additional RPO were given. After 2, 4 and 8 weeks of treatment, the catalase (CAT)activity results showed that there was no significant difference (P≥0.05) between the control group andthe treated groups. The mean value of the catalase activity after 2 weeks in control group for 5, 10, and15% were 1328, 1612, 1298 and 1270 U/mg, respectively. For superoxide dismutase (SOD), there was nosignificant difference (P≥0.05) between the control group and treated groups after 2 and 8 weeks oftreatment but there was significant difference (P≤0.05) in the 15% RPO group after 4 weeks.

Original languageEnglish
Pages (from-to)4651-4655
Number of pages5
JournalAfrican Journal of Biotechnology
Volume10
Issue number22
Publication statusPublished - 30 May 2011

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olein
enzyme activity
liver
Liver
rats
Enzymes
Control Groups
Catalase
catalase
Superoxide Dismutase
pellets
superoxide dismutase
Antioxidants
antioxidants

Keywords

  • Catalase
  • Red palm olein
  • Superoxide dismutase
  • Vitamin E

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Genetics
  • Molecular Biology
  • Agronomy and Crop Science

Cite this

Effect of different concentrations of red palm olein onantioxidant enzymes activity of rat liver. / Dauqan, Eqbal; Sani, Halimah Abdullah; Abdullah, Aminah; Mohd Kasim, Zalifah.

In: African Journal of Biotechnology, Vol. 10, No. 22, 30.05.2011, p. 4651-4655.

Research output: Contribution to journalArticle

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