Early post-traumatic seizures in children

Clinical and radiological aspects of injury

L. C. Ong, M. K. Dhillon, B. M. Selladurai, A. Maimunah, M. S. Lye

    Research output: Contribution to journalArticle

    38 Citations (Scopus)

    Abstract

    Objective: To determine the type and outcome of early post-traumatic seizures in children and the factors associated with it. Methodology: A prospective observational study on all consecutive children with head injuries at the General Hospital Kuala Lumpur between November 1993 and December 1994. The onset, type and frequency of seizures occurring within the first week of injury were documented. Using inpatients as a cohort, logistic regression analysis was used to determine clinical and radiological variables significantly associated with seizures. The outcome 6 months post-injury was assessed using the Glasgow Outcome Scale. Results: Fifty-three of 966 children (5.5%) developed seizures within the first week of trauma. Seven (13.2%) occurred with in 1 h of injury, 30 (56.6%) between 1 and 24 h and 16 (30.2%) after 24 h. Factors significantly associated with early post-traumatic seizures were female sex, age less than 2 years, loss of consciousness for more than 24 h and acute subdural haematoma (P<0.01). Children with seizures had a poorer outcome (death or severe disability) than inpatients without seizures (21/53 vs 19/182, P<0.001). The outcome was worst in children with recurrent partial seizures, who had a longer injury-seizure interval and were more likely to have focal neurologic deficits compared to those with sporadic or generalized seizures. Conclusions: Anticonvulsant prophylaxis to minimize the adverse effects of early seizures in head injury should be considered for young children (less than 2 years old) with subdural haematoma and a prolonged duration of coma. Prompt and effective control of recurrent seizures is recommended.

    Original languageEnglish
    Pages (from-to)173-176
    Number of pages4
    JournalJournal of Paediatrics and Child Health
    Volume32
    Issue number2
    Publication statusPublished - 1996

    Fingerprint

    Post-Traumatic Epilepsy
    Seizures
    Wounds and Injuries
    Craniocerebral Trauma
    Inpatients
    Hematoma, Subdural, Acute
    Glasgow Outcome Scale
    Subdural Hematoma
    Unconsciousness
    Coma
    Neurologic Manifestations
    General Hospitals
    Anticonvulsants
    Observational Studies

    Keywords

    • Children
    • Head injury
    • Seizures

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health

    Cite this

    Ong, L. C., Dhillon, M. K., Selladurai, B. M., Maimunah, A., & Lye, M. S. (1996). Early post-traumatic seizures in children: Clinical and radiological aspects of injury. Journal of Paediatrics and Child Health, 32(2), 173-176.

    Early post-traumatic seizures in children : Clinical and radiological aspects of injury. / Ong, L. C.; Dhillon, M. K.; Selladurai, B. M.; Maimunah, A.; Lye, M. S.

    In: Journal of Paediatrics and Child Health, Vol. 32, No. 2, 1996, p. 173-176.

    Research output: Contribution to journalArticle

    Ong, LC, Dhillon, MK, Selladurai, BM, Maimunah, A & Lye, MS 1996, 'Early post-traumatic seizures in children: Clinical and radiological aspects of injury', Journal of Paediatrics and Child Health, vol. 32, no. 2, pp. 173-176.
    Ong, L. C. ; Dhillon, M. K. ; Selladurai, B. M. ; Maimunah, A. ; Lye, M. S. / Early post-traumatic seizures in children : Clinical and radiological aspects of injury. In: Journal of Paediatrics and Child Health. 1996 ; Vol. 32, No. 2. pp. 173-176.
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