Early Dementia Questionnaire (EDQ)

A new screening instrument for early dementia in primary care practice

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: Worldwide, the population is ageing, resulting in an associated increase in dementia prevalence. Forgetfulness in elderly people is often perceived as normal in some local cultures and thus, the early detection of dementia in primary care requires detection of symptoms other than memory complaints.This study was conducted to screen elderly patients for early dementia in primary care using a newly developed Early Dementia Questionnaire (EDQ) and comparing it with a standard assessment tool, the Mini Mental State Examination (MMSE). Methods. A cross-sectional study was conducted on a group of elderly patients using convenience sampling of consecutive patients. Elderly depression was excluded using the Geriatric Depression Scale (GDS). Exclusion criteria also included known cases of dementia. Inclusion criteria included a score of 5 or less in GDS and the presence of a reliable informant. A face-to-face interview was done using the EDQ with the patient and informant to elicit symptoms of early dementia. If the informant was not present, a telephone interview was used instead. The patient was then assessed with the Mini Mental State Examination (MMSE) using a cut-off point of 21. Results: Prevalence of dementia among 155 subjects was 52.3% by EDQ and 15.5% by MMSE. The EDQ demonstrated a sensitivity of 79.2% with specificity of 52.7%. Positive predictive value (PPV) of EDQ was 23.5% with the negative predictive value (NPV) of 93.2%. The strongest predictor of possible early dementia was complaints of memory problems (OR 26.22; 95% CI 2.03-338.14) followed by complaints of concentration problems (OR 14.33; 95% CI 5.53-37.12), emotional problems (OR 4.75; 95% CI 1.64-13.81) and sleep disturbances (OR 3.14; 95% CI 1.15-8.56). Socio-demographic factors, medical problems and smoking status were not associated with possible dementia (p>0.05), despite that 60-70% of the elderly had chronic illnesses. Conclusion: The EDQ is a promising alternative to MMSE for screening of early dementia in primary care.

Original languageEnglish
Article number49
JournalBMC Family Practice
Volume14
DOIs
Publication statusPublished - 2013

Fingerprint

Dementia
Primary Health Care
Practice (Psychology)
Surveys and Questionnaires
Depression
Geriatrics
Interviews
Sleep
Chronic Disease
Cross-Sectional Studies
Smoking
Demography

Keywords

  • Dementia
  • Early dementia questionnaire
  • Mini mental state examination

ASJC Scopus subject areas

  • Family Practice

Cite this

@article{084cf7be130742749d68f8cf92ad8051,
title = "Early Dementia Questionnaire (EDQ): A new screening instrument for early dementia in primary care practice",
abstract = "Background: Worldwide, the population is ageing, resulting in an associated increase in dementia prevalence. Forgetfulness in elderly people is often perceived as normal in some local cultures and thus, the early detection of dementia in primary care requires detection of symptoms other than memory complaints.This study was conducted to screen elderly patients for early dementia in primary care using a newly developed Early Dementia Questionnaire (EDQ) and comparing it with a standard assessment tool, the Mini Mental State Examination (MMSE). Methods. A cross-sectional study was conducted on a group of elderly patients using convenience sampling of consecutive patients. Elderly depression was excluded using the Geriatric Depression Scale (GDS). Exclusion criteria also included known cases of dementia. Inclusion criteria included a score of 5 or less in GDS and the presence of a reliable informant. A face-to-face interview was done using the EDQ with the patient and informant to elicit symptoms of early dementia. If the informant was not present, a telephone interview was used instead. The patient was then assessed with the Mini Mental State Examination (MMSE) using a cut-off point of 21. Results: Prevalence of dementia among 155 subjects was 52.3{\%} by EDQ and 15.5{\%} by MMSE. The EDQ demonstrated a sensitivity of 79.2{\%} with specificity of 52.7{\%}. Positive predictive value (PPV) of EDQ was 23.5{\%} with the negative predictive value (NPV) of 93.2{\%}. The strongest predictor of possible early dementia was complaints of memory problems (OR 26.22; 95{\%} CI 2.03-338.14) followed by complaints of concentration problems (OR 14.33; 95{\%} CI 5.53-37.12), emotional problems (OR 4.75; 95{\%} CI 1.64-13.81) and sleep disturbances (OR 3.14; 95{\%} CI 1.15-8.56). Socio-demographic factors, medical problems and smoking status were not associated with possible dementia (p>0.05), despite that 60-70{\%} of the elderly had chronic illnesses. Conclusion: The EDQ is a promising alternative to MMSE for screening of early dementia in primary care.",
keywords = "Dementia, Early dementia questionnaire, Mini mental state examination",
author = "Zurraini Arabi and {Abd Aziz}, Noorazah and {Abdul Aziz}, {Aznida Firzah} and Rosdinom Razali and {Wan Puteh}, {Sharifa Ezat}",
year = "2013",
doi = "10.1186/1471-2296-14-49",
language = "English",
volume = "14",
journal = "BMC Family Practice",
issn = "1471-2296",
publisher = "BioMed Central",

}

TY - JOUR

T1 - Early Dementia Questionnaire (EDQ)

T2 - A new screening instrument for early dementia in primary care practice

AU - Arabi, Zurraini

AU - Abd Aziz, Noorazah

AU - Abdul Aziz, Aznida Firzah

AU - Razali, Rosdinom

AU - Wan Puteh, Sharifa Ezat

PY - 2013

Y1 - 2013

N2 - Background: Worldwide, the population is ageing, resulting in an associated increase in dementia prevalence. Forgetfulness in elderly people is often perceived as normal in some local cultures and thus, the early detection of dementia in primary care requires detection of symptoms other than memory complaints.This study was conducted to screen elderly patients for early dementia in primary care using a newly developed Early Dementia Questionnaire (EDQ) and comparing it with a standard assessment tool, the Mini Mental State Examination (MMSE). Methods. A cross-sectional study was conducted on a group of elderly patients using convenience sampling of consecutive patients. Elderly depression was excluded using the Geriatric Depression Scale (GDS). Exclusion criteria also included known cases of dementia. Inclusion criteria included a score of 5 or less in GDS and the presence of a reliable informant. A face-to-face interview was done using the EDQ with the patient and informant to elicit symptoms of early dementia. If the informant was not present, a telephone interview was used instead. The patient was then assessed with the Mini Mental State Examination (MMSE) using a cut-off point of 21. Results: Prevalence of dementia among 155 subjects was 52.3% by EDQ and 15.5% by MMSE. The EDQ demonstrated a sensitivity of 79.2% with specificity of 52.7%. Positive predictive value (PPV) of EDQ was 23.5% with the negative predictive value (NPV) of 93.2%. The strongest predictor of possible early dementia was complaints of memory problems (OR 26.22; 95% CI 2.03-338.14) followed by complaints of concentration problems (OR 14.33; 95% CI 5.53-37.12), emotional problems (OR 4.75; 95% CI 1.64-13.81) and sleep disturbances (OR 3.14; 95% CI 1.15-8.56). Socio-demographic factors, medical problems and smoking status were not associated with possible dementia (p>0.05), despite that 60-70% of the elderly had chronic illnesses. Conclusion: The EDQ is a promising alternative to MMSE for screening of early dementia in primary care.

AB - Background: Worldwide, the population is ageing, resulting in an associated increase in dementia prevalence. Forgetfulness in elderly people is often perceived as normal in some local cultures and thus, the early detection of dementia in primary care requires detection of symptoms other than memory complaints.This study was conducted to screen elderly patients for early dementia in primary care using a newly developed Early Dementia Questionnaire (EDQ) and comparing it with a standard assessment tool, the Mini Mental State Examination (MMSE). Methods. A cross-sectional study was conducted on a group of elderly patients using convenience sampling of consecutive patients. Elderly depression was excluded using the Geriatric Depression Scale (GDS). Exclusion criteria also included known cases of dementia. Inclusion criteria included a score of 5 or less in GDS and the presence of a reliable informant. A face-to-face interview was done using the EDQ with the patient and informant to elicit symptoms of early dementia. If the informant was not present, a telephone interview was used instead. The patient was then assessed with the Mini Mental State Examination (MMSE) using a cut-off point of 21. Results: Prevalence of dementia among 155 subjects was 52.3% by EDQ and 15.5% by MMSE. The EDQ demonstrated a sensitivity of 79.2% with specificity of 52.7%. Positive predictive value (PPV) of EDQ was 23.5% with the negative predictive value (NPV) of 93.2%. The strongest predictor of possible early dementia was complaints of memory problems (OR 26.22; 95% CI 2.03-338.14) followed by complaints of concentration problems (OR 14.33; 95% CI 5.53-37.12), emotional problems (OR 4.75; 95% CI 1.64-13.81) and sleep disturbances (OR 3.14; 95% CI 1.15-8.56). Socio-demographic factors, medical problems and smoking status were not associated with possible dementia (p>0.05), despite that 60-70% of the elderly had chronic illnesses. Conclusion: The EDQ is a promising alternative to MMSE for screening of early dementia in primary care.

KW - Dementia

KW - Early dementia questionnaire

KW - Mini mental state examination

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