Display of the antigenic region of Nipah virus nucleocapsid protein on hepatitis B virus capsid

Wei Boon Yap, Beng Ti Tey, Noorjahan Banu Mohamed Alitheen, Wen Siang Tan

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The C-terminal domain of Nipah virus (NiV) nucleocapsid protein (NP 401-532) was inserted at the N-terminus and the immunodominant loop of hepatitis B core antigen (HBc). The stability of NP 401-532 increased tremendously when displayed on the HBc particles. These particles reacted specifically with the swine anti-NiV and the human anti-HBc antisera.

Original languageEnglish
Pages (from-to)26-29
Number of pages4
JournalJournal of Bioscience and Bioengineering
Volume113
Issue number1
DOIs
Publication statusPublished - Jan 2012
Externally publishedYes

Fingerprint

Nipah Virus
Hepatitis B Core Antigens
Nucleocapsid Proteins
Capsid
Antigens
Viruses
Hepatitis B virus
Display devices
Proteins
Hepatitis B Antibodies
Immune Sera
Swine

Keywords

  • Hepatitis B core antigen
  • Hepatitis B virus
  • Nipah virus
  • Nucleocapsid protein
  • Virus-like particles

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Bioengineering

Cite this

Display of the antigenic region of Nipah virus nucleocapsid protein on hepatitis B virus capsid. / Yap, Wei Boon; Tey, Beng Ti; Mohamed Alitheen, Noorjahan Banu; Tan, Wen Siang.

In: Journal of Bioscience and Bioengineering, Vol. 113, No. 1, 01.2012, p. 26-29.

Research output: Contribution to journalArticle

Yap, Wei Boon ; Tey, Beng Ti ; Mohamed Alitheen, Noorjahan Banu ; Tan, Wen Siang. / Display of the antigenic region of Nipah virus nucleocapsid protein on hepatitis B virus capsid. In: Journal of Bioscience and Bioengineering. 2012 ; Vol. 113, No. 1. pp. 26-29.
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